Antibiotic regimens for postpartum endometritis

The Cochrane Database of Systematic Reviews
A Dhanya MackeenLinda Speer

Abstract

Postpartum endometritis occurs when vaginal organisms invade the endometrial cavity during the labor process and cause infection. This is more common following cesarean birth. The condition warrants antibiotic treatment. Systematically, to review treatment failure and other complications of different antibiotic regimens for postpartum endometritis. We searched the Cochrane Pregnancy and Childbirth Group's Trials Register (30 November 2014) and reference lists of retrieved studies. We included randomized trials of different antibiotic regimens after cesarean birth or vaginal birth; no quasi-randomized trials were included. Two review authors independently assessed trials for inclusion and risk of bias, extracted data and checked them for accuracy. The review includes a total of 42 trials, and 40 of these trials contributed data on 4240 participants.Regarding the primary outcomes, seven studies compared clindamycin plus an aminoglycoside versus penicillins and showed fewer treatment failures (risk ratio (RR) 0.65, 95% confidence interval (CI) 0.46 to 0.90). There were more treatment failures in those treated with an aminoglycoside plus penicillin when compared to those treated with gentamycin/clindamycin (RR 2.57, 95% CI 1.48 to ...Continue Reading

References

Aug 15, 1979·American Journal of Obstetrics and Gynecology·A K KreutnerC B Loadholt
Jul 1, 1992·American Journal of Obstetrics and Gynecology·R R MacGregorP Samuels
Apr 1, 1990·Southern Medical Journal·M G MartensM Maccato
Feb 1, 1989·American Journal of Obstetrics and Gynecology·G G BriggsM P Nageotte
Jan 1, 1989·Supplement to International Journal of Gynecology and Obstetrics·S ScalambrinoM P Canale
Jul 1, 1989·Diagnostic Microbiology and Infectious Disease·M G MartensM Maccato
Sep 1, 1989·American Journal of Obstetrics and Gynecology·W J MoralesR A Knuppel
Jan 1, 1989·Supplement to International Journal of Gynecology and Obstetrics·J A McGregor, F B Christensen
Jan 1, 1988·European Journal of Clinical Pharmacology·J BiollazJ L Schelling
Feb 1, 1987·American Journal of Obstetrics and Gynecology·W R CrombleholmeR L Sweet
Feb 1, 1988·American Journal of Obstetrics and Gynecology·R D AlvarezJ F Huddleston
Mar 1, 1988·American Journal of Obstetrics and Gynecology·D L HemsellR L Sweet
Sep 1, 1987·Southern Medical Journal·J G PastorekS K Nicaud
Aug 1, 1985·American Journal of Obstetrics and Gynecology·R L SweetM O Robbie
Jan 1, 1982·The Journal of Antimicrobial Chemotherapy·J R MarshallT C Sorrell
Sep 1, 1982·Reviews of Infectious Diseases·D L HemsellT T Miller
May 1, 1980·Obstetrics and Gynecology·R S Gibbs
Apr 15, 1982·American Journal of Obstetrics and Gynecology·P Duff, J F Keiser
Jan 15, 1982·American Journal of Obstetrics and Gynecology·R S GibbsY S Castaneda
Dec 1, 1980·American Journal of Obstetrics and Gynecology·G P WagerK K Holmes
Feb 10, 1996·BMJ : British Medical Journal·M BarzaJ Lau
Jun 1, 1996·Obstetrics and Gynecology·G Del PrioreM C Frederiksen
Feb 1, 1997·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·D L HemsellJ A McGregor
Nov 20, 1998·American Journal of Obstetrics and Gynecology·M A TurnquestH L Brown
Nov 8, 2002·Acta Obstetricia Et Gynecologica Scandinavica·Bo JacobssonJens Jörgen Platz-Christensen
Jan 28, 2003·American Journal of Obstetrics and Gynecology·Jeffrey C LivingstonBaha Sibai
Oct 3, 2003·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Joseph S SolomkinUNKNOWN Infectious Diseases Society of America
Oct 21, 2004·The Cochrane Database of Systematic Reviews·L M French, F M Smaill

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Citations

Jul 18, 2018·The Cochrane Database of Systematic Reviews·David M HaasSavannah Enders
Jul 6, 2018·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Michal Fishel BartalIsrael Hendler
Apr 27, 2020·The Cochrane Database of Systematic Reviews·David M HaasSavannah Kimball
Dec 15, 2018·The Cochrane Database of Systematic Reviews·Jacquelyn GrevRoger Soll
Jul 12, 2017·Maternal Health, Neonatology and Perinatology·Tetsuya Kawakita, Helain J Landy
Dec 1, 2017·The Cochrane Database of Systematic Reviews·Mercedes BonetOlufemi T Oladapo
Aug 1, 2019·Pharmacy : Journal of Pharmacy, Education and Practice·Saira B ChaudhryJamie L Wagner
Apr 30, 2020·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Inshirah SgayerMaya Frank Wolf
May 12, 2021·Deutsches Ärzteblatt International·Susanne Schrey-PetersenHolger Stepan

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