Antibiotic resistance in patients after serial intravitreal injections

Vestnik oftalmologii
G V VoroninA S Khalatyan

Abstract

Despite the lack of convincing data on the effectiveness of antibiotic therapy in the prevention of Post-Injection Endophthalmitis (PIE), the use of topical antibiotics for intravitreal injections is still a common practice. Frequent, monthly use of antibiotics results in changes of the composition of conjunctival flora and spontaneous mutations of bacteria, and leads to selective survival of resistant and virulent strains that can cause serious damage inside the eye.

References

Oct 16, 2004·Retina·Lloyd P AielloMichael T Trese
Sep 23, 2006·American Journal of Ophthalmology·Vincent A DeramoIra J Udell
Oct 6, 2006·The New England Journal of Medicine·Philip J RosenfeldUNKNOWN MARINA Study Group
Sep 25, 2007·Journal of Cataract and Refractive Surgery·David F ChangUNKNOWN ASCRS Cataract Clinical Committee
Feb 12, 2014·Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie·Stephen J DorrepaalSanjay Sharma
Mar 19, 2014·Ophthalmic Surgery, Lasers & Imaging Retina·John B FiletaHarry W Flynn
May 6, 2015·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Philip StoreyUNKNOWN Post-Injection Endophthalmitis Study Team
May 28, 2019·Ophthalmology Retina·Rahul ChaturvediDaniel L Chao

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