Antibiotic-resistant enterococci and the changing face of surgical infections

Archives of Surgery
M E de Vera, R L Simmons

Abstract

Enterococci have not been thought to play an important role in intra-abdominal infections because of their relatively low virulence. However, this notion is changing because of the recent emergence of these microbes as significant nosocomial pathogens. To review the mechanisms of antibiotic resistance of enterococci and to discuss the significance of multidrug-resistant enterococci in surgical infections. Medical and basic science literature relating to enterococci. In addition to having intrinsic resistance to a number of antibiotics, enterococci have the ability to acquire resistant genes through the exchange of plasmids or transposons from other bacterial species. Moreover, enterococci have been shown to transmit these genes to other bacterial species in turn. The extensive resistance of these microorganisms has led to their emergence as significant nosocomial pathogens, ranking second only to Escherichia coli in the number of pathogenic isolates recovered from patients in intensive care units. There has also been a marked increase in vancomycin-resistant enterococcal infections in surgical patients in the last 5 years. Some studies associate the prior use of vancomycin or third-generation cephalosporins with the emergence o...Continue Reading

Citations

Aug 17, 2001·Veterinary Microbiology·P BoerlinP Schawalder
Dec 20, 2003·American Journal of Surgery·Mark A Wilson
Feb 1, 1997·American Journal of Infection Control·F L Cohen, D Tartasky
Dec 1, 1996·American Journal of Surgery·D H Wittmann, M Schein
Jul 31, 1998·The American Journal of Medicine·R L Nichols
Jun 26, 2015·Surgical Infections·Torsten HerzogAnsgar M Chromik
Apr 28, 2007·International Journal of Surgery·Peter FominUNKNOWN Three Hundred Six Study Group
Jun 28, 2003·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Renato Satovschi GrinbaumRosangela Ferraz Cereda
Apr 18, 2012·Scandinavian Journal of Gastroenterology·Torsten HerzogChristophe A Mueller
Jan 31, 1998·The Surgical Clinics of North America·M S Farber, J H Abrams

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