PMID: 6968146Aug 1, 1980Paper

Antibiotic sensitivity of Haemophilus influenzae strains including three recent chloramphenicol-resistant isolates

Acta Pathologica Et Microbiologica Scandinavica. Section B, Microbiology
G Zackrisson, J E Brorson

Abstract

The antibiotic sensitivity of 100 recent isolates of Haemophilus influenzae was determined. Three strains were resistant to chloramphenicol with minimal inhibitory concentrations of 16 microgram/ml. Of these three resistant strains, one produced betalactamase and one was resistant to sulfamethoxazole-trimethoprim. The remaining strains were inhibited by 0.25-2.0 microgram/ml of chloramphenicol. Ampicillin and benzylpenicillin were found to inhibit all but the betalactamase-producing strains at low concentrations. Regarding sulfamethoxazole-trimethoprim 96% had minimal inhibitory concentrations of 2.5-0.12 microgram/ml or less, while two strains were resistant. The invitro efficacy of erythromycin against H. influenzae was low. The majority of the strains was inhibited by low concentrations of doxycycline and cefuroxime while cefoxitin exhibited minimal inhibitory concentrations values usually exceeding 1 microgram/ml. The minimal inhibitory concentrations registered are compared to the concentrations of the different antibiotics attainable in certain body fluids.

References

Jul 1, 1977·Acta Oto-laryngologica·C Carenfelt, C Lundberg
Mar 27, 1976·Lancet·A MantenM Dessens-Kroon
Jan 1, 1975·Scandinavian Journal of Infectious Diseases·O KalmO Norman
Mar 18, 1978·British Medical Journal·A L KinmonthR G Mitchell
Mar 1, 1977·Antimicrobial Agents and Chemotherapy·B van KlingerenM Dessens-Kroon
Mar 1, 1977·Antimicrobial Agents and Chemotherapy·G D OverturfP F Wehrle
Jul 1, 1979·Antimicrobial Agents and Chemotherapy·R Yogev, T Williams
Nov 1, 1979·The Journal of Antimicrobial Chemotherapy·A Svedhem, S Iwarson
May 1, 1978·The Journal of Antimicrobial Chemotherapy·S IwarsonR Svensson
Sep 1, 1978·The Journal of Pediatrics·B I AsmarA S Dajani
Jan 1, 1975·Acta paediatrica Scandinavica·K G Sabel, A Brandberg
Mar 1, 1976·Antimicrobial Agents and Chemotherapy·R NorrbyS Seeberg
Apr 1, 1972·Antimicrobial Agents and Chemotherapy·C H O'CallaghanA H Shingler
Sep 27, 1967·Annals of the New York Academy of Sciences·L H TaberF G Nieberg
Aug 12, 1972·British Medical Journal·J R May, J Davies
Jan 26, 1974·British Medical Journal·J D Williams, J Andrews
May 1, 1968·The Journal of Pediatrics·J D Coffey
Jan 1, 1960·Scandinavian Journal of Clinical and Laboratory Investigation·H ERICSSON

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