Antibiotic stewardship (ABS). Part 1: Basics

Der Internist
S WendtC Lübbert

Abstract

Against the background of increasing antimicrobial resistance, antibiotic stewardship (ABS) is an important measure to counteract the spread of resistant pathogens and multidrug resistance. For Germany and Austria, a comprehensive S3 guideline is available, which was last updated in 2018. The control of antibiotic or anti-infective use in hospitals should be guided by specialized ABS teams. At the hospital level, ABS also includes a structured ongoing analysis of local antibiotic use and resistance data. Recommendations for locally adapted therapy regimens should be derived and implemented from this data analysis. ABS consists of regular ward rounds ("ABS visits"), during which members of the ABS team review the indication, dosage, route of administration and duration of antimicrobial therapy at the bedside. Here, the key challenge is to save antibiotics without compromising the individual patient. Digitalization and artificial intelligence offer new options for ABS, while the adaption of inpatient concepts to outpatient care is also important.

References

Apr 20, 2006·Journal of the American Medical Informatics Association : JAMIA·Jessina C McGregorAnthony D Harris
Feb 22, 2012·International Journal of Antimicrobial Agents·Ursula Theuretzbacher
Nov 26, 2015·Lancet·Alison H HolmesLaura J V Piddock
Aug 6, 2017·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·C PulciniM Mendelson
Dec 26, 2017·The Lancet Infectious Diseases·Evelina TacconelliUNKNOWN WHO Pathogens Priority List Working Group
Mar 28, 2018·Proceedings of the National Academy of Sciences of the United States of America·Eili Y KleinRamanan Laxminarayan

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