PMID: 9442491Jan 1, 1997Paper

Antibiotic susceptibility of group A streptococci in 2 Italian cities: Milano and Catania

Microbial Drug Resistance : MDR : Mechanisms, Epidemiology, and Disease
C E CocuzzaG Nicoletti

Abstract

Resistance to macrolides has increasingly been reported for Group A streptococci. In this study, the in vitro antibiotic susceptibility pattern of 305 clinical isolates of S. pyogenes was determined. Strains were isolated during 1996 from pharyngeal swabs of children with uncomplicated pharyngitis living in 2 Italian cities: Milano and Catania, situated in the North and South of Italy, respectively. All isolates were found to be fully susceptible to penicillin and other beta-lactam agents tested. Susceptibility to macrolides differed markedly between the two centers with relatively high resistance rates to erythromycin being observed in Milano (30%) as compared to Catania (3%). Resistance to erythromycin was always crossed with that of the other 14- and 15-membered macrolides tested. However, resistance to josamycin and clindamycin was generally found in approximately 25% of the erythromycin-resistant (ER) strains. The erythromycin-resistant isolates from Milano and Catania (58 strains) were further subdivided into the three previously described resistance phenotypes: constitutive, inducible, and novel resistance phenotypes. The novel resistance phenotype accounted for 58% of all resistant strains, while 17% and 26% were found ...Continue Reading

References

Jan 30, 1992·The New England Journal of Medicine·H SeppäläT Klaukka
Feb 1, 1991·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·E L Kaplan
Jul 1, 1991·Antimicrobial Agents and Chemotherapy·R Leclercq, P Courvalin
Jan 1, 1990·Scandinavian Journal of Infectious Diseases·L HolmströmT Ripa
Jan 1, 1988·Scandinavian Journal of Infectious Diseases·G ZackrissonP Larsson
Jun 1, 1995·Pediatric Clinics of North America·M A Gerber
Jul 1, 1994·The Pediatric Infectious Disease Journal·K M Coonan, E L Kaplan
Dec 1, 1993·The Journal of Antimicrobial Chemotherapy·H SeppäläP Huovinen
Nov 1, 1996·Antimicrobial Agents and Chemotherapy·J SutcliffeL Wondrack

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Citations

Apr 30, 1999·Emerging Infectious Diseases·E Perez-TralleroM de Pablos
Apr 11, 2000·Emerging Infectious Diseases·M BassettiD Bassetti
Jul 12, 2005·General and Comparative Endocrinology·B Hareramadas, U Rai
Sep 6, 2000·Letters in Applied Microbiology·K BosioD Savoia
Apr 30, 1999·Emerging Infectious Diseases·M BassettiD Bassetti
Nov 24, 1999·Microbial Drug Resistance : MDR : Mechanisms, Epidemiology, and Disease·J Melo-Cristino, M L Fernandes

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