Antibiotic usage in surgical prophylaxis: A prospective observational study in the surgical ward of Nekemte referral hospital

PloS One
Getachew Alemkere

Abstract

Surgical antimicrobial prophylaxis guidelines are considered as important interventional tools for antimicrobial resistance. Guideline compliance was poor across different countries and thus results in an inappropriate and overuse of antibiotics. To evaluate the selection, timing and duration of prophylactic antibiotic administration among surgical patients in Nekmte referral hospital. Prospective, facility based cross-sectional study was conducted from 1st April to 30th June 2017. Data were collected using data abstraction format among surgical inpatients prescribed with surgical antibiotic prophylaxis. Surgical antimicrobial prophylaxis guidelines were used as data assessment protocols. SPSS version 21.0 was used for data entry and analysis. Descriptive statistics and binary logistic regression were used for analysis. The median age of the study participants was 35.0 (IQR: 25-50) years with the preponderance (58.8%) of male patients. The median hospitalization period was 8.0 (IQR: 5-11) days. Majority of the participants were from the general surgical ward (60.1%). About 43% of the procedures were clean. Most of the surgical cases were gastrointestinal (39.2%). Only 10.6% of the drug selections comply with American Society of...Continue Reading

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Citations

Mar 3, 2021·International Journal of Clinical Pharmacy·Nurlina MulianiHeru Wijono
Jul 6, 2021·JAC-antimicrobial Resistance·Courtney IeranoCaroline Marshall

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