Antibiotic use on paediatric inpatients in a teaching hospital in the Gambia, a retrospective study

Antimicrobial Resistance and Infection Control
Pa Saidou ChawRafael Mikolajczyk

Abstract

Antibiotics are useful but increasing resistance is a major problem. Our objectives were to assess antibiotic use and microbiology testing in hospitalized children in the Gambia. We conducted a retrospective analysis of paediatric inpatient data at The Edward Francis Small Teaching Hospital in Banjul, The Gambia. We extracted relevant data from the admission folders of all patients (aged > 28 days to 15 years) admitted in 2015 (January-December), who received at least one antibiotic for 24 h. We also reviewed the microbiology laboratory record book to obtain separate data for the bacterial isolates and resistance test results of all the paediatric inpatients during the study period. Over half of the admitted patients received at least one antibiotic during admission (496/917) with a total consumption of 670.7 Days of Antibiotic Therapy/1000 Patient-Days. The clinical diagnoses included an infectious disease for 398/496, 80.2% of the patients on antibiotics, pneumonia being the most common (184/496, 37.1%). There were 51 clinically relevant bacterial isolates, Klebsiella species being the most common (12/51, 23.5%), mainly from urine (11/12, 91.7%). Antibiotic resistance was mainly to ampicillin (38/51, 74.5%), mainly reported a...Continue Reading

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Citations

Mar 3, 2020·Journal of Chemotherapy·Ioana D OlaruKatharina Kranzer
May 28, 2020·The American Journal of Tropical Medicine and Hygiene·Boubacar CoulibalyCatherine E Oldenburg
Oct 1, 2021·Expert Review of Anti-infective Therapy·Zia Ul MustafaSyed Shahzad Hasan

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