PMID: 6170735Aug 1, 1981Paper

Antibiotics and antivirals do not modify experimentally-induced Creutzfeldt-Jakob disease in mice

Journal of Neurology, Neurosurgery, and Psychiatry
J Tateishi

Abstract

Thiamphenicol, rifampicin, amantadine, cytosine arabinoside and isoprinosine were administered to mice which were inoculated with brain tissue containing Creutzfeldt-Jakob disease (CJD). All the mice developed disease within 3 to 6 months after inoculation. As there was no significant shift in incubation periods among animal groups of each drug administration and non-administration, these compounds had no effect in controlling experimental CJD.

References

Oct 6, 1979·Lancet·W B MatthewsJ T Hughes
Oct 1, 1979·Journal of Neurology, Neurosurgery, and Psychiatry·W L Sanders
May 1, 1979·Japanese Circulation Journal·T OdaH Morinaga
Aug 1, 1973·Journal of Neurology, Neurosurgery, and Psychiatry·W L Sanders, T L Dunn

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Citations

Jan 1, 1994·Molecular Aspects of Medicine·M Pocchiari

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