Antibiotics for community-acquired pneumonia in children

The Cochrane Database of Systematic Reviews
R LodhaRavindra M Pandey

Abstract

Pneumonia caused by bacterial pathogens is the leading cause of mortality in children in low-income countries. Early administration of antibiotics improves outcomes. To identify effective antibiotic drug therapies for community-acquired pneumonia (CAP) of varying severity in children by comparing various antibiotics. We searched CENTRAL 2012, Issue 10; MEDLINE (1966 to October week 4, 2012); EMBASE (1990 to November 2012); CINAHL (2009 to November 2012); Web of Science (2009 to November 2012) and LILACS (2009 to November 2012). Randomised controlled trials (RCTs) in children of either sex, comparing at least two antibiotics for CAP within hospital or ambulatory (outpatient) settings. Two review authors independently extracted data from the full articles of selected studies. We included 29 trials, which enrolled 14,188 children, comparing multiple antibiotics. None compared antibiotics with placebo.Assessment of quality of study revealed that 5 out of 29 studies were double-blind and allocation concealment was adequate. Another 12 studies were unblinded but had adequate allocation concealment, classifying them as good quality studies. There was more than one study comparing co-trimoxazole with amoxycillin, oral amoxycillin with ...Continue Reading

References

Jan 1, 1976·The Journal of International Medical Research·R Mouallem
Sep 1, 1984·The Journal of Antimicrobial Chemotherapy·I E Haffejee
Jul 1, 1993·Kansenshōgaku zasshi. The Journal of the Japanese Association for Infectious Diseases·N IshiwadaH Niimi
Apr 1, 1996·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·O GrigoriouL Giannikos
Dec 1, 1995·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·F Shann
Sep 1, 1996·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·T J PhillipsV Lordan
May 1, 1997·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·D GendrelG Kalifa
Nov 5, 1998·The Pediatric Infectious Disease Journal·J A HarrisM R Hammerschlag
Feb 27, 1999·The Pediatric Infectious Disease Journal·L WubbelG H McCracken
Dec 20, 1999·The Journal of Antimicrobial Chemotherapy·F A Al-EidanJ Jenkins
Feb 19, 2000·Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology·R S MaitreyiA K Prasad
Sep 23, 2000·The Pediatric Infectious Disease Journal·G H McCracken
Apr 4, 2001·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·H PeltolaUNKNOWN SE-TU Study Group
Sep 24, 2002·Lancet·UNKNOWN Pakistan Multicentre Amoxycillin Short Course Therapy (MASCOT) pneumonia study group
Mar 7, 2003·Indian Journal of Pediatrics·S K KabraR S Maitreyi
Sep 5, 2003·The Lancet Infectious Diseases·Sunil SazawalUNKNOWN Pneumonia Case Management Trials Group
Feb 12, 2004·The Pediatric Infectious Disease Journal·Daniel E NoyolaJ Raúl Ochoa-Zavala
Dec 2, 2004·Indian Journal of Pediatrics·Feyzullah CetinkayaGunsel Kutluk
May 7, 2005·The Pediatric Infectious Disease Journal·Susanna EspositoNicola Principi

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Citations

Dec 15, 2017·Journal of Clinical Microbiology·C M C Rodrigues, H Groves
May 24, 2018·Paediatrics and International Child Health·Shrey MathurMike Sharland
Dec 27, 2013·The Cochrane Database of Systematic Reviews·Amy Millicent Y CaoMieke L van Driel
Aug 14, 2019·BMJ Global Health·Joseph MillumCarla Saenz
Sep 22, 2018·Current Infectious Disease Reports·Samriti GuptaS K Kabra
Nov 21, 2020·Archives of Disease in Childhood. Education and Practice Edition·Sarah Murphy, Louise Thomson
Dec 3, 2021·Indian Journal of Pediatrics·Arpita ChattopadhyayRakesh Lodha

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