Antibiotics for gram-positive bacterial infections: vancomycin, quinupristin-dalfopristin, linezolid, and daptomycin

Infectious Disease Clinics of North America
Tammy S Lundstrom, Jack D Sobel

Abstract

An overview of the mechanism of action, dosing, clinical indications, and toxicities of the glycopeptide vancomycin is provided. Emerging gram-positive bacterial resistance to antimicrobials and its mechanisms are reviewed. Strategies to control emergence of resistance are proposed. Newer antimicrobial agents with activity against vancomycin-resistant organisms are now available and play a critical role in the treatment of life-threatening infections.

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Related Concepts

Synercid
Antibiotics
AB-Vancomycin
Staphylomycin
Gram-Positive Bacterial Infections
Daptomycin,9-L beta-Aspartic Acid

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