Jul 23, 2008

Antibiotics for preventing complications in children with measles

The Cochrane Database of Systematic Reviews
Sushil K KabraDeborah J Hilton

Abstract

Measles is the leading killer among vaccine-preventable diseases, responsible for an estimated 44% of the 1.7 million vaccine-preventable deaths among children annually. To assess the effects of antibiotics given to children with measles to prevent complications and reduce pneumonia, other morbidities and mortality. In this 2008 update we searched the Cochrane Central Register of Controlled Trials (The Cochrane Library 2008, Issue 1) MEDLINE (1966 to January week 1, 2008), EMBASE (1980 to December 2007) and the National Research Register (Issue 3, 2007). Randomized controlled trials (RCTs) and quasi-RCTs comparing antibiotics with placebo or no treatment to prevent complications in children with measles. Two review authors independently extracted data and assessed trial quality. Seven trials with 1385 children were included. Pooled study data showed that the incidence of pneumonia was lower in the treatment group compared to the control group. However, the difference was not statistically significant. In children who received antibiotics, 1.9% developed pneumonia, while in the control group 6% developed pneumonia (OR 0.28; 95% CI 0.06 to 1.25). The one trial that showed an increase in the rate of pneumonia with antibiotics was ...Continue Reading

  • References
  • Citations3

References

  • We're still populating references for this paper, please check back later.

Mentioned in this Paper

Bacterial Conjunctivitis
Meta-Analysis (Publications)
Spasmodic Croup
Bacteriocidal Agents
Antibiotic throat preparations
Antifungal Antibiotics, Topical
Transcription Initiation
Sulfathiazole
Antibiotics, Gynecological
Controlled Clinical Trials, Randomized

Related Feeds

Antifungals

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

Antifungals (ASM)

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.