Antibiotics in primary care in England: which antibiotics are prescribed and for which conditions?

The Journal of Antimicrobial Chemotherapy
F Christiaan K DolkTimo Smieszek

Abstract

To analyse antibiotic prescribing behaviour in English primary care with particular regard to which antibiotics are prescribed and for which conditions. Primary care data from 2013-15 recorded in The Health Improvement Network (THIN) database were analysed. Records with a prescription for systemic antibiotics were extracted and linked to co-occurring diagnostic codes, which were used to attribute prescriptions to clinical conditions. We further assessed which antibiotic classes were prescribed and which conditions resulted in the greatest share of prescribing. The prescribing rate varied considerably among participating practices, with a median of 626 prescriptions/1000 patients (IQR 543-699). In total, 69% of antibiotic prescriptions (n = 3 156 507) could be linked to a body system and/or clinical condition. Of these prescriptions, 46% were linked to conditions of the respiratory tract, including ear, nose and throat (RT/ENT); leading conditions within this group were cough symptoms (22.7%), lower respiratory tract infection (RTI) (17.9%), sore throat (16.7%) and upper RTI (14.5%). After RT/ENT infections, infections of the urogenital tract (22.7% of prescriptions linked to a condition) and skin/wounds (16.4%) accounted for th...Continue Reading

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Citations

Mar 1, 2018·The Journal of Antimicrobial Chemotherapy·Timo SmieszekJulie V Robotham
Mar 1, 2018·The Journal of Antimicrobial Chemotherapy·Koen B PouwelsJulie V Robotham
Mar 1, 2018·The Journal of Antimicrobial Chemotherapy·Koen B PouwelsTimo Smieszek
Mar 1, 2018·The Journal of Antimicrobial Chemotherapy·David R M SmithTimo Smieszek
Feb 3, 2018·The Journal of Antimicrobial Chemotherapy·Koen B PouwelsTimo Smieszek
Jun 7, 2018·The Journal of Infectious Diseases·Stefan Flasche, Katherine E Atkins
Dec 19, 2018·Journal of Medical Microbiology·Robert William O'HaraMathew Upton
Apr 20, 2019·The Journal of Antimicrobial Chemotherapy·Kevin L SchwartzGary Garber
May 1, 2019·The Journal of Antimicrobial Chemotherapy·Victoria PalinTjeerd van Staa
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