Antibiotics in the treatment of gastroenteritis caused by enteropathogenic Escherichia coli

The Journal of Infectious Diseases
A ThorénD Habte

Abstract

The role of antibiotics in treating endemic infantile diarrhea caused by enteropathogenic Escherichia coli has not been determined. In a controlled study of 49 patients, one group received mecillinam and another group received trimethoprim-sulfamethoxazole. A third group served as control subjects. Serotype O111:B4 dominated. Treatment, as evaluated clinically on the third day, resulted in cure for 79% of those receiving mecillinam, 73% of those receiving trimethoprim-sulfamethoxazole, and 7% of the control subjects. Bacteriologic cure was confirmed in 53%, 53%, and 0, respectively. The statistically significant difference between antibiotic-treated patients and control subjects (P less than 0.001) indicated that antibiotics are an important supplement in the treatment of endemic severe diarrhea caused by enteropathogenic E. coli.

Citations

Nov 1, 1987·Indian Journal of Pediatrics·P Aggarwal, M Singh
Jun 1, 1993·Baillière's Clinical Gastroenterology·D A Scott, R Edelman
Dec 1, 1991·Mayo Clinic Proceedings·F R Cockerill, R S Edson
Apr 2, 1988·Lancet·S M HillP J Milla
Sep 1, 1992·Acta Paediatrica. Supplement·M E Penny
Aug 29, 1983·The American Journal of Medicine·C H Demos, E Green
Apr 1, 1986·Disease-a-month : DM·T C QuinnJ G Bartlett
May 1, 1992·Pharmacological Research : the Official Journal of the Italian Pharmacological Society·M CastelliI Galatulas
Jan 1, 1983·Scandinavian Journal of Infectious Diseases. Supplementum·A Thorén
Nov 1, 1982·Acta paediatrica Scandinavica·B L PerssonM Walder
Sep 1, 1986·American Journal of Hematology·B H BjornsonA I Tauber
Oct 21, 2017·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Ferric C Fang, Robin Patel
Apr 27, 2018·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Robert J CybulskiFerric C Fang
Aug 1, 1989·Alimentary Pharmacology & Therapeutics·A D Pithie, C J Ellis
Sep 1, 1984·Annals of Tropical Paediatrics·M K MackenjeeR M Robins-Browne
Oct 1, 1980·Acta Pathologica Et Microbiologica Scandinavica. Section B, Microbiology·A Thorén
Feb 15, 2001·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·R L GuerrantInfectious Diseases Society of America

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FL-1060
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