Antibodies to GM1 and GD1b in patients with motor neuron disease without plasma cell dyscrasia

Annals of Neurology
M E ShyT G DeRyk

Abstract

Fifty-nine percent of 49 patients with motor neuron disease and 25% of 91 control subjects had IgM antibodies to ganglioside GM1 but usually not to GD1b at titers less than 1:80. This suggests that antibodies to GM1 may be part of the normal human antibody repertoire. However, given the higher incidence of antibodies to GM1 in patients with motor neuron disease, there may be specific epitopes important in antiganglioside antibodies associated with motor neuron disease.

References

Feb 1, 1985·The Journal of Clinical Investigation·R S Schwartz, B D Stollar
Nov 1, 1986·Neurology·M E ShyE F Osserman
Jan 1, 1984·Journal of Neuroscience Research·G GazzottiG Tettamanti
Jan 1, 1982·Methods in Enzymology·R W Ledeen, R K Yu

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Citations

Jan 1, 1990·Annals of Neurology·N Latov
Apr 1, 1994·Annals of Neurology·H J WillisonJ Veitch
Oct 1, 1992·Journal of Neurology·M WellerH Wiethölter
Sep 15, 1994·Biochimica Et Biophysica Acta·L SvennerholmB M Rynmark
Oct 15, 1993·Journal of Immunological Methods·F ChabraouiC Caudie
Mar 10, 1994·Journal of Immunological Methods·M H RavindranathM C Graves
Aug 1, 1991·Journal of the Neurological Sciences·P S FishmanD A Kristt
Sep 1, 1993·Journal of the Neurological Sciences·S H AppelE Stefani
Jul 1, 1994·Journal of the Neurological Sciences·S H AppelE Stefani
Jul 1, 1994·Journal of the Neurological Sciences·S A SmithS P Ringel
Sep 1, 1994·Journal of Neuroimmunology·E Nobile-OrazioG Scarlato
Jul 7, 2001·Journal of the Neurological Sciences·S OnoH Nakagawa
Dec 1, 1992·Acta Neurologica Scandinavica·C VoumvourakisC Papageorgiou
Apr 1, 1994·Journal of Clinical Pathology·A S BansalP B Wilson
Apr 1, 1993·Journal of Neurology, Neurosurgery, and Psychiatry·A StevensH Wiethölter
Nov 1, 1994·Journal of Neurology, Neurosurgery, and Psychiatry·H J Willison
Apr 1, 1991·Journal of Neurosurgery·F A RoddenB L Bauer
Mar 1, 1995·Journal of Neuroimmunology·A Ben Younes-ChennoufiV Meininger
Jan 1, 1997·Cancer Investigation·M H Ravindranath, D L Morton
Jun 30, 2012·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Suraj Ashok Muley, Gareth J Parry
May 3, 2008·Clinical Neurology and Neurosurgery·Toshihiro YamazakiSeiitsu Ono
Nov 22, 2007·Biochimica Et Biophysica Acta·Gustavo A NoresFernando J Irazoqui
Mar 7, 2013·The International Journal of Neuroscience·Arzu ÇobanHalil Atilla Idrisoğlu
Feb 24, 2001·Neuropathology : Official Journal of the Japanese Society of Neuropathology·S Petratos, M E Gonzales
Nov 1, 1989·Annals of Neurology·M A MeyerL T Kurland

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