Antibodies to the leucine-rich repeat region of internalin block entry of Listeria monocytogenes into cells expressing E-cadherin.

Infection and Immunity
J MengaudPascale Cossart

Abstract

Internalin, a surface protein essential for entry of Listeria monocytogenes EGD into epithelial cells, was used as an antigen to raise nine monoclonal antibodies. These monoclonal antibodies recognized seven distinct epitopes which were located in three different regions of the protein. Three of them inhibited internalin-mediated entry and recognized the amino-terminal leucine-rich repeat region of the protein, suggesting that this region is essential for entry.

References

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Citations

Mar 19, 2002·Cellular Microbiology·Javier Pizarro-CerdáPascale Cossart
Apr 4, 2002·Molecular Microbiology·Hélène BierneUNKNOWN European Listeria Genome Consortium
May 7, 2009·Cellular Microbiology·Emilia Moreno-RuizEsteban Veiga
Mar 24, 2010·Infection and Immunity·Divya IyerJanina P Lewis
Aug 18, 2010·Periodontology 2000·Ashu Sharma
Dec 29, 2010·International Journal of Inflammation·Markus Schuppler, Martin J Loessner
Feb 6, 2014·PLoS Neglected Tropical Diseases·Karen EvangelistaJenifer Coburn
Jul 22, 2014·Molecular Oral Microbiology·C Anaya-BergmanJ P Lewis
Aug 30, 2000·Proceedings of the National Academy of Sciences of the United States of America·M LecuitP Cossart
May 13, 2009·Molecular Microbiology·C JungV Orian-Rousseau
Jun 23, 2009·Microbiology·Roy D SleatorCormac G M Gahan
Aug 23, 2005·Infection and Immunity·Armelle BigotCatherine Raynaud
Sep 1, 2004·The Journal of Cell Biology·Stéphanie SeveauPascale Cossart
Feb 24, 2010·Infection and Immunity·Nicolas PersonnicHélène Bierne
Sep 26, 2001·The Journal of Cell Biology·H BierneP Cossart
Feb 22, 2003·Infection and Immunity·Fernanda da Silva TatleyParry J Guilford
Feb 26, 2004·Molecular Microbiology·Claire BonnemainAlain Charbit
Mar 12, 2008·Molecular Microbiology·Marieluise Kirchner, Darren E Higgins
Mar 19, 2004·Journal of Bacteriology·Hélène BierneAlain Charbit
Nov 7, 2016·Cell Communication and Signaling : CCS·María Fernanda Izaguirre, Victor Hugo Casco
Feb 21, 2002·Infection and Immunity·Caroline GarandeauAlain Charbit
Jul 2, 2004·Molecular Microbiology·S DramsiP Cossart

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