PMID: 7539088Oct 1, 1994Paper

Antibody-induced alterations of protein and nucleic acid metabolism during experimental thyroglobulin immunization

Methods and Findings in Experimental and Clinical Pharmacology
S Lahiri, A Chakraborty

Abstract

The protein and nucleic acid contents of liver, spleen, muscle, kidney, and brain were studied in experimental autoimmune thyroiditis. Protein and ribonucleic acid levels showed a positive increase in the case of liver, spleen, and muscle on days 56 and 98 after immunization and on day 147 they reached control levels. Spleen deoxyribonucleic acid showed a significant increase on day 56, whereas the other days showed no change. Kidney and brain tissue revealed no change.

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