PMID: 6991897Feb 1, 1980Paper

Antibody levels in mothers colonised with group B streptococci during pregnancy and in their newborn infants, as measured by an enzyme linked immunosorbent assay

Medical Microbiology and Immunology
P H CleatJ R Needham

Abstract

An enzyme-linked immunosorbent assay (ELISA) was developed to measure serum antibodies to group B streptococci in 20 healthy pregnant women before delivery and in their newborn infants. The sera from 10 of these women who were colonised with group B streptococci and umbilical cord sera from their infants, had higher levels of type-specific IgG antibody than the 10 non-colonised controls and their neonates. All the babies remained well. The results demonstrate that infants from colonised mothers receive type-specific antibody. The possibility that this antibody may provide some degree of protection at birth against this potentially lethal organism warrants investigation.

References

Feb 1, 1976·The Journal of Experimental Medicine·C J BakerC E Davis
Aug 1, 1977·The Journal of Infectious Diseases·C J Baker, D L Kasper
Nov 1, 1977·The Journal of Infectious Diseases·P B Stewardson-KriegerS P Gotoff
Jun 1, 1978·Journal of Clinical Pathology·A VollerD E Bidwell

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Citations

Jan 1, 1980·Medical Microbiology and Immunology·P H Cleat, C R Coid
Sep 1, 1987·Culture, Medicine and Psychiatry·R Littlewood, M Lipsedge
Jan 1, 1982·Infection and Immunity·D O Fleming

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