Anticancer Effects of Herbal Medicine Compounds and Novel Formulations: a Literature Review.

Journal of Gastrointestinal Cancer
Manal Khalid AbdulridhaAbdolmajid Ghasemian

Abstract

Many agents disrupt the cell cycle and its signaling circuits leading to cancer progress. Cancer therapy is performed by surgery, radiation, and chemical drugs remaining some side effects. To evaluate the anticancer traits of herbal medicines. We collected previously published data in searching engines (Web of Science, PubMed, Medline, and SCOPUS) by searching key words "herbal medicine," "anticancer effect," "compounds," and "fractions." Herbal medicines have unraveled anticancer effects mostly through cancer cells apoptosis via blocking NF-κB pathway by curcumin and terpenoides; CD95 signaling and enhancement of CD95L expression by resveratrol; and inhibiting tyrosine kinas, angiogenesis, and cell cycle arrest in G2/M phase by β-lapachone-genistein and cytochrome-c release into the cytosol and caspase-9 activation by biocalein and quercetin. Additionally, impeding cell cycle in the G1 phase in ovarian cancer cells by 7-hydroxystaurosporine, immune cells enrichment (neutrophils and NK cells activation by Viscum album L., T cells and NK cells activation and cytokines such as tumor necrosis factor release by Ganoderma lucidum and microRNAs regulation (by Sinomeniumacutum, shikonin, Oleaeuropaea, curcumin and ginseng). These effe...Continue Reading

References

Jan 31, 2002·Annual Review of Medicine·Michael M Gottesman
Jan 31, 2004·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Elena J LadasKara M Kelly
Jul 13, 2005·Journal of Ethnopharmacology·Gordon M Cragg, David J Newman
Jan 20, 2006·The New England Journal of Medicine·James D Yager, Nancy E Davidson
Mar 25, 2006·Phytotherapy Research : PTR·S HemaIswarya, Mukesh Doble
Feb 21, 2007·Journal of Natural Products·David J Newman, Gordon M Cragg
Dec 14, 2011·Nutrition and Cancer·Bokyung SungBharat B Aggarwal
Feb 3, 2012·The American Journal of Chinese Medicine·Jeong Won HwangJong-Soon Choi
Feb 10, 2012·Journal of Natural Products·David J Newman, Gordon M Cragg
Nov 15, 2012·Journal of Ethnobiology and Ethnomedicine·Carsten Smith-HallMariève Pouliot
Nov 20, 2012·Annual Review of Immunology·Guido KroemerLaurence Zitvogel
Dec 15, 2012·Experimental Biology and Medicine·Raimundo Fernandes de Araújo JúniorGerlane Coelho Bernardo Guerra
Jan 1, 2013·Journal of Ethnopharmacology·Qiuhong WangKelvin Chan
Apr 16, 2013·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Jung-Hye ShinDawon Kang
Oct 2, 2013·Annual Review of Pathology·Gianpiero Di LevaCarlo M Croce
Nov 1, 2013·Nature Reviews. Drug Discovery·Hui LingGeorge A Calin
Nov 19, 2013·Anti-cancer Agents in Medicinal Chemistry·Georgia Schäfer, Catherine H Kaschula
Mar 13, 2014·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Parisa KarimiFarin Kamangar
Dec 5, 2014·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Elio RossiAlberto Zanobini
May 12, 2015·Journal of Immunology Research·Rodrigo ArreolaDaniel Ortuño-Sahagún
Apr 6, 2016·Cancer Letters·Mohammed L AbbaHeike Allgayer
Oct 27, 2016·Natural Product Reports·Zhong Jin
Dec 23, 2016·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·Ali MohammadiBehzad Baradaran
Jan 27, 2017·Experimental and Therapeutic Medicine·Qin WangJianbin Sun
Apr 19, 2017·Journal of Traditional and Complementary Medicine·Rizwan AhmadMastour Safer Al-Ghamdi
Jul 8, 2017·Current Medicinal Chemistry·Manee Patanapongpibul, Qiao-Hong Chen
Dec 14, 2017·Evidence-based Complementary and Alternative Medicine : ECAM·Yao KouJing Tian
Jan 31, 2018·Critical Reviews in Food Science and Nutrition·Murphy L Y WanM F Wang
Aug 15, 2018·International Journal of Molecular Sciences·Bahare SalehiJavad Sharifi-Rad

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Jul 1, 2020·European Journal of Medicinal Chemistry·Yucen TaoPeng Zhan

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