PMID: 2504122Aug 1, 1989Paper

Anticardiolipin antibodies in acquired immunodeficiency syndrome

Archives of Internal Medicine
M M StimmlerO P Sharma

Abstract

We undertook a prospective study of IgG and IgM anticardiolipin antibodies (ACAs) to determine their clinical significance in patients with acquired immunodeficiency syndrome (AIDS). IgG ACAs were found in 24 (92.3%) of 26 patients with AIDS who were hospitalized for pulmonary complaints (group 1) and in 13 (93%) of 14 patients with AIDS-related complex (group 2). In addition, 17 (94%) of 18 patients with AIDS (group 3) who had coagulation tests and were studied retrospectively had IgG ACAs. The prevalence of IgG ACAs in these three groups was significantly higher than in healthy controls, but was comparable to that in 31 consecutive patients with systemic lupus erythematosus (67.7%). The mean titer of IgG ACAs in group 1 was higher than in groups 2 and 3 but was not different from that in the patients with systemic lupus erythematosus. The frequency and titer of IgM ACAs in group 1 (7.6%) or group 2 (14.3%) were not significantly different from those in normal controls (4.7%). In contrast, half of the patients in group 3 had low-titer IgM ACAs. The serum titer of IgG ACAs in patients with AIDS with thrombocytopenia was significantly higher than it was in those with normal platelet counts. There was no association between ACAs ...Continue Reading

Citations

May 1, 1991·Annals of the Rheumatic Diseases·J RiveraL Carreño
Sep 12, 2008·AIDS Patient Care and STDs·Nancy F Crum-CianfloneMary Bavaro
Apr 20, 2010·Journal of Clinical Immunology·Peter I LoboHong Pei
May 27, 2003·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Pierre AbgueguenEric Pichard
Sep 1, 1996·The American Journal of Medicine·B J Brew, J Miller
Jun 1, 1992·The American Journal of the Medical Sciences·D M BeckerD C Schain
Nov 20, 2012·Journal of the Chinese Medical Association : JCMA·Ta-I WangTain-Hsiung Chen
Oct 1, 1993·Journal of the American Academy of Dermatology·O BayrouF Leynadier
Aug 2, 2006·Rheumatic Diseases Clinics of North America·Maria G Tektonidou, Haralampos M Moutsopoulos
May 8, 1998·Seminars in Arthritis and Rheumatism·K E HansenA J Bridges
Apr 1, 1990·Journal of Autoimmunity·A M Krieg, A D Steinberg
May 20, 1998·Journal of the American Academy of Dermatology·L RequenaA Barat
Feb 1, 1997·Journal of the American Academy of Dermatology·G T Nahass
May 1, 1997·Rheumatic Diseases Clinics of North America·B J Fessler
Mar 12, 2003·Hematology/oncology Clinics of North America·Rodger L Bick
Sep 13, 2015·Best Practice & Research. Clinical Rheumatology·Christine Fox, Karen Walker-Bone
Nov 22, 2002·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·J D Woolgar, J V Robbs
Jan 8, 2013·Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology·Eli Ben-ChetritDana G Wolf
Feb 18, 2008·The Neuroradiology Journal·Hung-Wen KaoGuo-Shu Huang
Oct 16, 2010·Lupus·S V Navarra, M S N Leynes
Aug 11, 1991·Stroke; a Journal of Cerebral Circulation·S F AmerisoM Fisher
Oct 11, 1992·Stroke; a Journal of Cerebral Circulation·S F AmerisoM Fisher
Nov 1, 1996·Stroke; a Journal of Cerebral Circulation·R F MackoM Fisher
Jul 14, 2006·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Alexandra M LevineHoward A Liebman
May 1, 1991·Annals of the Rheumatic Diseases·A D BlannM I Jayson
May 1, 1991·Annals of the Rheumatic Diseases·R Lagier, J C Gerster
Nov 8, 2001·Clinical and Applied Thrombosis/hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis·R L Bick
Apr 25, 2000·Indian Journal of Pediatrics·A Kakar, P K Sethi
Jun 6, 2008·Journal of Clinical Rheumatology : Practical Reports on Rheumatic & Musculoskeletal Diseases·Taoufik HarzyWafaa Bono
May 1, 1994·Infection·A LafeuilladeN Profizi
Mar 3, 2007·Clinical Rheumatology·Liliana GalrãoMittermayer Santiago
May 3, 2008·Clinical Chemistry·Willem M LijferingJan van der Meer
Dec 31, 1997·AIDS·P S MassabkiL E Andrade
Aug 22, 2016·Rheumatology International·Justyna Roszkiewicz, Elzbieta Smolewska
Nov 18, 2010·Blood Pressure·Thomas HednerIngrid Os

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