PMID: 9542442May 16, 1998Paper

Anticipating rotavirus vaccines: review of epidemiologic studies of rotavirus diarrhea in Argentina

Revista Panamericana De Salud Pública = Pan American Journal of Public Health
J A GómezR I Glass

Abstract

Rotavirus is the most common cause of severe diarrhea in children worldwide, and vaccines currently being field-tested could be available for childhood immunization in several years. To assess the rotavirus disease burden in Argentina and the value of future national surveillance for the disease, we reviewed available data on rotavirus detections reported by published and unpublished studies conducted in nine Argentine cities and by a multicenter study. Data from these studies indicated that rotavirus was detected in 20% of 5,226 specimens (within a range of 6% to 54% for different studies) from children hospitalized for diarrhea and in 9% of 6,587 specimens (within a range of 5% to 22% for different studies) from children who were outpatients, members of mixed populations (hospitalized patients and outpatients), or survey subjects in community-based studies. The hospital data showed that while rotavirus was detected throughout the year, a peak occurred during the winter months (May-July) when up to half of the children with diarrhea were found positive for rotavirus. Attempted serotyping of 294 rotavirus-positive specimens for G-protein by three laboratories was successful in 230 cases (78%); the resulting data indicated that ...Continue Reading

Citations

Apr 9, 1999·Vaccine·R M Jacobson
Jan 13, 2001·BMJ : British Medical Journal·P Abrams
Aug 28, 2015·The Science of the Total Environment·V E PrezP A Barril
Dec 20, 2011·Tropical Medicine & International Health : TM & IH·Jennifer CortesKim A Lindblade
Sep 10, 2002·The Journal of Infection·Nigel A CunliffeC Anthony Hart
Sep 15, 2001·Revista Do Instituto De Medicina Tropical De São Paulo·M O GiordanoS V Nates
Jan 2, 2007·The Pediatric Infectious Disease Journal·Miguel O'RyanClelia Vallebuono
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Sep 15, 2007·Journal of Medical Virology·Karina A GomesGabriel I Parra
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Oct 27, 2004·The Pediatric Infectious Disease Journal·F Raúl VelázquezPablo Kuri

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