Anticipation of interoceptive threat in highly anxiety sensitive persons

Behaviour Research and Therapy
Christiane A MelzigAlfons O Hamm

Abstract

Anticipatory anxiety plays a major role in the etiology of panic disorder. Although anticipatory anxiety elicited by expectation of interoceptive cues is specifically relevant for panic patients, it has rarely been studied. Using a population analogue in high fear of such interoceptive arousal sensations (highly anxiety sensitive persons) we evaluated a new experimental paradigm to assess anticipatory anxiety during anticipation of interoceptive (somatic sensations evoked by hyperventilation) and exteroceptive (electric shock) threat. Symptom reports, autonomic arousal, and defensive response mobilization (startle eyeblink response) were monitored during threat and matched safe conditions in 26 highly anxiety sensitive persons and 22 controls. The anticipation of exteroceptive threat led to a defensive and autonomic mobilization as indexed by a potentiation of the startle response and an increase in skin conductance level in both experimental groups. During interoceptive threat, however, only highly anxiety sensitive persons but not the controls exhibited a startle response potentiation as well as autonomic activation. The anticipation of a hyperventilation procedure thus seems a valid paradigm to investigate anticipatory anxie...Continue Reading

References

Jan 1, 1989·Behaviour Research and Therapy·C D Donnell, R J McNally
Jan 1, 1986·Behaviour Research and Therapy·D M Clark
Jul 1, 1985·Archives of General Psychiatry·M R LiebowitzS O Davies
Sep 1, 1971·Psychophysiology·D T Lykken, P H Venables
Jul 1, 1969·Psychophysiology·G E Deane
Dec 1, 1984·Journal of Consulting and Clinical Psychology·D L ChamblessR Gallagher
Aug 1, 1981·Psychological Medicine·B K TooneM H Lader
Apr 1, 1994·Biological Psychiatry·C GrillonM Davis
Nov 1, 1996·Psychophysiology·A O Hamm, D Vaitl
Sep 15, 1997·Biological Psychiatry·C GrillonM Davis
Dec 23, 1998·Biological Psychiatry·P J LangB N Cuthbert
Feb 16, 2000·Journal of the American Academy of Child and Adolescent Psychiatry·C HaywardC B Taylor
Mar 24, 2000·Neuroscience Letters·Y Masaoka, I Homma
Feb 13, 2001·Journal of Affective Disorders·P J LangA Ohman
Feb 24, 2001·Psychological Review·M E BoutonD H Barlow
Aug 4, 2001·Psychosomatic Medicine·F H WilhelmW T Roth
Jan 29, 2002·Respiration Physiology·Y Masaoka, I Homma
Nov 20, 2002·Biological Psychiatry·Richard J McNally
Sep 2, 2003·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Christian Grillon, Johanna Baas
Jun 1, 1961·Journal of Experimental Psychology·G E DEANE
May 21, 2004·Nature Reviews. Neuroscience·George B Richerson
Feb 22, 2005·Psychophysiology·Terry D BlumenthalAnton van Boxtel
Jun 18, 2005·European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology·Hans-Ulrich Wittchen, Frank Jacobi
Oct 24, 2007·Journal of Anxiety Disorders·Eileen WollburgSunyoung Kim
Aug 30, 2008·Behaviour Research and Therapy·Christiane A MelzigAlfons O Hamm

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Citations

Nov 28, 2013·Neurobiology of Learning and Memory·Mathias WeymarPeter J Lang
Sep 15, 2012·Social Cognitive and Affective Neuroscience·Yuri TerasawaSatoshi Umeda
Apr 2, 2013·International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology·Erik CeunenIlse Van Diest
Jan 29, 2014·Brain Research·Kai MacDonald, David Feifel
Feb 7, 2016·Progress in Neuro-psychopharmacology & Biological Psychiatry·Mu-Hong Chen, Shih-Jen Tsai
Jan 24, 2012·International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology·Meike PappensIlse Van Diest
Mar 9, 2010·Neuroscience Letters·Mitsuo IshidaMasanori Nagai
Nov 16, 2010·Psychophysiology·Christiane A MelzigAlfons O Hamm
Jul 30, 2010·Psychophysiology·Peter J LangVincent D Costa
Feb 16, 2012·Psychophysiology·Meike PappensIlse Van Diest
Jul 26, 2015·International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology·Erik CeunenIlse Van Diest
Apr 10, 2012·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Mathias WeymarPeter J Lang
May 12, 2015·Biological Psychology·Martin RiemerGeorg W Alpers
Mar 31, 2015·Psychiatry Research·Jose M MartinezJack M Gorman
Dec 5, 2014·Psychopharmacology·Christiane A Pané-FarréAlfons O Hamm
Jan 5, 2011·International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology·André SchulzHartmut Schächinger
Mar 24, 2012·NeuroImage·Katharina HoltzAlfons O Hamm
May 14, 2016·Drug and Alcohol Dependence·Stephanie M GorkaStewart A Shankman
Aug 30, 2008·Behaviour Research and Therapy·Christiane A MelzigAlfons O Hamm
Oct 22, 2016·Psychophysiology·Georgiana JuravleAndreas von Leupoldt
Apr 25, 2018·Behavior Modification·Katharina HoltzChristiane A Pané-Farré
Jan 13, 2017·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·André SchulzHartmut Schächinger
Sep 21, 2016·Neural Plasticity·M Cornelia StoeckelAndreas von Leupoldt
May 28, 2019·Frontiers in Physiology·Yafei TanAndreas von Leupoldt
Jan 2, 2018·Journal of Anxiety Disorders·Elizabeth S StevensStewart A Shankman
Jun 10, 2018·Biological Psychiatry : Cognitive Neuroscience and Neuroimaging·Elischa KrauseChristiane A Pané-Farré
Nov 13, 2021·The European Journal of Neuroscience·Yuri TerasawaYoshiya Moriguchi
Dec 23, 2021·PloS One·Steven DaveyElliot Bell

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