Sep 1, 1984

Anticoagulant activity of dextran derivatives. Part I: Synthesis and characterization

Biomaterials
M Mauzac, J Jozefonvicz

Abstract

Substituted dextrans bearing carboxymethyl and benzylsulphonate groups have been prepared. These materials exhibit an antithrombic activity correlated with the ratio of each substituent. The highest activity is obtained when the dextran derivative contains more than 50% of carboxylic acid groups and simultaneously about 15% of benzylsulphonate functions.

  • References8
  • Citations64

References

Mentioned in this Paper

Thrombin Time Assay
Structure-Activity Relationship
Anticoagulant Activity
Dextrans
Indirect Thrombin Inhibitors
Dextran
Carboxylic Acids
Saviosol

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