Anticoagulants for acute ischaemic stroke.

The Cochrane Database of Systematic Reviews
Peter Ag SandercockEdward J Kane

Abstract

Most ischaemic strokes are caused by a blood clot blocking an artery in the brain. Clot prevention with anticoagulants might improve outcomes if bleeding risks are low. This is an update of a Cochrane review first published in 1995, with recent updates in 2004 and 2008. To assess the effectiveness and safety of early anticoagulation (within the first 14 days of onset) in people with acute presumed or confirmed ischaemic stroke. We searched the Cochrane Stroke Group Trials Register (June 2014), the Cochrane Central Register of Controlled Trials (CENTRAL), the Cochrane Database of Systematic Reviews (CDSR), the Database of Reviews of Effects (DARE) and the Health Technology Assessment Database (HTA) (The Cochrane Library 2014 Issue 6), MEDLINE (2008 to June 2014) and EMBASE (2008 to June 2014). In addition, we searched ongoing trials registries and reference lists of relevant papers. For previous versions of this review, we searched the register of the Antithrombotic Trialists' (ATT) Collaboration, consulted MedStrategy (1995), and contacted relevant drug companies. Randomised trials comparing early anticoagulant therapy (started within two weeks of stroke onset) with control in people with acute presumed or confirmed ischaemic s...Continue Reading

Associated Clinical Trials

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Citations

Jan 24, 2017·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Donna KurowskiBrett Cucchiara
May 22, 2019·Current Atherosclerosis Reports·Brian Mac GroryShadi Yaghi
Feb 19, 2016·The Cochrane Database of Systematic Reviews·Bian LiuMing Liu
Sep 20, 2018·Current Neurology and Neuroscience Reports·Paula Muñoz VenturelliPhilip M Bath
Sep 30, 2020·Translational Stroke Research·Fenghui YeGuohua Xi
Jul 15, 2020·The Cochrane Database of Systematic Reviews·Liliya Eugenevna ZiganshinaCharles Hv Hoyle
Feb 27, 2017·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Danilo ToniVito Toso
Jul 28, 2019·Intensive Care Medicine·M SmithG Citerio
May 19, 2020·Current Pharmaceutical Design·Paraskevi PapanikolaouDimitris Tousoulis
Oct 31, 2020·Cellular and Molecular Neurobiology·Chengli LiuWei Wang

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