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Anticonvulsant effects of diazepam and MK-801 in soman poisoning

Epilepsy Research

Nov 1, 1990

T M Shih

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Abstract

An animal model was developed to evaluate the anticonvulsant effects of diazepam and MK-801 in soman poisoning and to examine the possible mechanism of soman-induced convulsions. The oxime HI-6 (125 mg/kg, i.p.) was given to male rats, to increase survival, 30 min prior to 180 microgram...read more

Mentioned in this Paper

Anticholinergic [EPC]
Atropine Sulfate Anhydrous
Antidote
Diazepam
MK-801
Dose-Response Relationship, Drug
Metazoa
Pyridinium Compounds
Dizocilpine
Anticholinergic Agents
Paper Details
References
  • References31
  • Citations48
  • References31
  • Citations48
12345

Anticonvulsant effects of diazepam and MK-801 in soman poisoning

Epilepsy Research

Nov 1, 1990

T M Shih

PMID: 2289469

DOI: 10.1016/0920-1211(90)90095-d

Abstract

An animal model was developed to evaluate the anticonvulsant effects of diazepam and MK-801 in soman poisoning and to examine the possible mechanism of soman-induced convulsions. The oxime HI-6 (125 mg/kg, i.p.) was given to male rats, to increase survival, 30 min prior to 180 microgram...read more

Mentioned in this Paper

Anticholinergic [EPC]
Atropine Sulfate Anhydrous
Antidote
Diazepam
MK-801

Related Papers

Paper Details
References
  • References31
  • Citations48
  • References31
  • Citations48
12345

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