journal cover

Anticonvulsant efficacy of antihistamine cyproheptadine in rats exposed to the chemical warfare nerve agent soman

Neurotoxicology

Jan 1, 2017

Jennifer L WinklerRobert K Kan

PMID: 27988303

DOI: 10.1016/j.neuro.2016.12.004

Get paper from

Abstract

Organophosphate compounds, such as soman and sarin, are highly toxic chemical warfare nerve agents that cause a build-up of acetylcholine in synapses and neuromuscular junctions. Current therapies aim to prevent seizures and protect against brain injury following exposure. The present s...read more

Mentioned in this Paper

In Situ Nick-End Labeling
Synapses
Acetylcholine Measurement
Viternum
Cell Death
Study
Evaluation
Dose-Response Relationship, Drug
Methylatropine nitrate
Metazoa
Paper Details
References
  • References25
  • Citations1
123
  • References25
  • Citations1
1

Similar Papers Found In These Feeds

Brain Injury & Trauma

brain injury after impact to the head is due to both immediate mechanical effects and delayed responses of neural tissues.

Formation of Synapses and Circuits

Synapses are crucial for the transmission of information within neural circuits. These specialized intercellular junctions are the basis for the formation of complex networks. Formation of these synapses involve numerous steps that are essential for transmission of information. Here is the latest research on formation of synapses and circuits.

Synaptic Junctions

Synaptic or neuronal junctions are the site of transmission of electrical nerve impulses between neurons or between neurons and effector cells. Discover the latest research on synaptic junctions here.

Addiction

This feed focuses mechanisms underlying addiction and addictive behaviour including heroin and opium dependence, alcohol intoxication, gambling, and tobacco addiction.

Pharmacological Treatment of Allergies

Allergies, also known as allergic diseases, are a number of conditions caused by hypersensitivity of the immune system to typically harmless substances in the environment. There are various pharmacological treatments for allergy including antihistamines, anti-cholinergics, decongestants, etc. Discover the latest research on pharmacological treatment of allergies here.

Apoptosis

Apoptosis is a specific process that leads to programmed cell death through the activation of an evolutionary conserved intracellular pathway leading to pathognomic cellular changes distinct from cellular necrosis

ContactHelpTerms Privacy Cookies
© 2019 Meta ULC. All rights reserved

Anticonvulsant efficacy of antihistamine cyproheptadine in rats exposed to the chemical warfare nerve agent soman

Neurotoxicology

Jan 1, 2017

Jennifer L WinklerRobert K Kan

PMID: 27988303

DOI: 10.1016/j.neuro.2016.12.004

Abstract

Organophosphate compounds, such as soman and sarin, are highly toxic chemical warfare nerve agents that cause a build-up of acetylcholine in synapses and neuromuscular junctions. Current therapies aim to prevent seizures and protect against brain injury following exposure. The present s...read more

Mentioned in this Paper

In Situ Nick-End Labeling
Synapses
Acetylcholine Measurement
Viternum
Cell Death

Similar Papers Found In These Feeds

Related Papers

Paper Details
References
  • References25
  • Citations1
123
  • References25
  • Citations1
1

Get paper from

/papers/anticonvulsant-efficacy-of-antihistamine/27988303