Antidepressant and antipsychotic agents

Die Naturwissenschaften
R A Lahti

Abstract

Numerous studies have been reviewed concerning the relationship of the catecholamines and indoleamines to depression and its treatment with antidepressant drugs. The profusion of data on the subject suggests the amines may be implicated in the disease, however no convincing hypothesis is available which unites the two. A similar situation seems to exist concerning the antipsychotic agents, dopamine and schizophrenia. The evidence appears to be overwhelming relating dopamine in the action of these agents and yet serious inconsistencies have been reported suggesting the need for a revision of the hypothesis regarding the mode of action of antipsychotic agents.

References

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Citations

May 1, 1991·Medical Hypotheses·L Benusková
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Related Concepts

Thymoleptics
Brain
Catecholamines
Depressive Symptoms
Endorphins
Norepinephrine, (+, -)-Isomer
Alpha-adrenergic receptor
Hydroxytryptamine
Structure-Activity Relationship
Antipsychotic Effect

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