Antidepressant use before and after initiation of diabetes mellitus treatment.

Diabetologia
M J KnolE R Heerdink

Abstract

Although current literature suggests an association between diabetes and depression, the direction of the association is unclear. We examined the temporal association between diabetes and depression by studying antidepressant and benzodiazepine use around the initiation of diabetes treatment. From a pharmacy registry database we selected 49,593 diabetic patients and a random sample of non-diabetic individuals (n = 154,441), all >40 years old. Antidepressant and benzodiazepine use was calculated for the 7 years before and 7 years after the index date. The index date in diabetes patients was defined as the date of initiation of diabetes medication. A random index date was assigned to non-diabetic individuals. Time-specific incidence rate ratios of antidepressant and benzodiazepine use were calculated for intervals of 1 year, 3 months and 1 month. Antidepressant and benzodiazepine use was increased 2 months before and 3 months after the initiation of diabetes treatment compared with non-diabetic individuals. The strongest increase in incidence of antidepressant and benzodiazepine use was seen in the month after initiation of diabetes treatment with incidence rate ratios of 2.4 (95% CI 2.0-3.0) and 3.4 (95% CI 3.0-3.8) respectively...Continue Reading

References

Apr 1, 1992·Journal of Epidemiology and Community Health·R M HeringsG Nap
Feb 1, 1992·Journal of Clinical Epidemiology·M Von KorffK Saunders
Jul 1, 1991·Diabetic Medicine : a Journal of the British Diabetic Association·L A PalinkasD L Wingard
Jun 13, 1994·Archives of Internal Medicine·M Olfson, H A Pincus
Oct 3, 2001·The British Journal of Psychiatry : the Journal of Mental Science·C ThompsonA L Kinmonth
Jul 31, 2004·Acta Psychiatrica Scandinavica·M van den AkkerF Buntinx
Oct 23, 2004·Diabetic Medicine : a Journal of the British Diabetic Association·L A PalinkasE Barrett-Connor
Apr 28, 2005·Diabetes Care·Lauren C BrownJeffrey A Johnson
Jun 16, 2005·Archives of Internal Medicine·Daniel PolskyChristy L Thompson
Dec 24, 2005·Expert Opinion on Drug Safety·Roger S McIntyreSidney H Kennedy
Jul 5, 2006·CMAJ : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne·Lauren C BrownJeffrey A Johnson
Sep 8, 2006·Journal of Affective Disorders·H GardarsdottirA C G Egberts
Oct 24, 2006·Diabetic Medicine : a Journal of the British Diabetic Association·S AliK Khunti
May 2, 2007·Psychosomatic Medicine·Mirjam J KnolHuibert Burger
Oct 6, 2007·International Clinical Psychopharmacology·Mirjam J KnolEibert R Heerdink
Sep 17, 2008·American Journal of Epidemiology·Mirjam J KnolMatthias Egger

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Citations

Nov 29, 2012·Current Opinion in Psychiatry·Michael Deuschle
Aug 22, 2013·Psychological Medicine·K ManderbackaM Elovainio
Nov 3, 2010·Plastic and Reconstructive Surgery·Frank FangKevin C Chung
Jun 19, 2013·Health & Place·Briana MezukKristina Sundquist
Mar 14, 2014·The Lancet. Diabetes & Endocrinology·Adam G TabákMika Kivimäki
Dec 26, 2012·Diabetes Research and Clinical Practice·F Rotella, E Mannucci
Jun 22, 2014·Community Mental Health Journal·Syed Shahzad HasanTherese Kairuz
Sep 28, 2016·World Journal of Gastroenterology : WJG·Mohammad S KhurooMehnaaz S Khuroo
Nov 21, 2018·Journal of Clinical Medicine·Rasha ElamoshyJohn Moraros

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