Antidepressants for insomnia in adults.

The Cochrane Database of Systematic Reviews
Hazel EverittSue Wilson

Abstract

Insomnia disorder is a subjective condition of unsatisfactory sleep (e.g. sleep onset, maintenance, early waking, impairment of daytime functioning). Insomnia disorder impairs quality of life and is associated with an increased risk of physical and mental health problems including anxiety, depression, drug and alcohol abuse, and increased health service use. hypnotic medications (e.g. benzodiazepines and 'Z' drugs) are licensed for sleep promotion, but can induce tolerance and dependence, although many people remain on long-term treatment. Antidepressant use for insomnia is widespread, but none is licensed for insomnia and the evidence for their efficacy is unclear. This use of unlicensed medications may be driven by concern over longer-term use of hypnotics and the limited availability of psychological treatments. To assess the effectiveness, safety and tolerability of antidepressants for insomnia in adults. This review incorporated the results of searches to July 2015 conducted on electronic bibliographic databases: the Cochrane Central Register of Controlled Trials (CENTRAL, 2015, Issue 6), MEDLINE (1950 to 2015), Embase (1980 to 2015) and PsycINFO (1806 to 2015). We updated the searches to December 2017, but these results h...Continue Reading

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Citations

Mar 6, 2019·European Journal of Clinical Pharmacology·Raquel MerinoRosa Terré
Dec 14, 2019·Sleep & Breathing = Schlaf & Atmung·Ali PourmotabbedMaryam Miraghajani
Jul 5, 2018·Drug and Therapeutics Bulletin
Nov 13, 2019·BMC Complementary and Alternative Medicine·Yu ZhongShanshan Liu
Nov 12, 2019·Deutsches Ärzteblatt International·Jan RémiPeter Young
Mar 16, 2021·European Geriatric Medicine·E P van PoelgeestN van der Velde
Jul 2, 2021·Deutsches Ärzteblatt International·Peter MaiselNorbert Donner-Banzhoff

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