PMID: 12787964Jun 6, 2003Paper

Antidiabetic activity of a standardized extract (Glucosol) from Lagerstroemia speciosa leaves in Type II diabetics. A dose-dependence study

Journal of Ethnopharmacology
William V JudyRichard Passwater

Abstract

The antidiabetic activity of an extract from the leaves of Lagerstroemia speciosa standardized to 1% corosolic acid (Glucosol) has been demonstrated in a randomized clinical trial involving Type II diabetics (non-insulin-dependent diabetes mellitus, NIDDM). Subjects received a daily oral dose of Glucosol and blood glucose levels were measured. Glucosol at daily dosages of 32 and 48mg for 2 weeks showed a significant reduction in the blood glucose levels. Glucosol in a soft gel capsule formulation showed a 30% decrease in blood glucose levels compared to a 20% drop seen with dry-powder filled hard gelatin capsule formulation (P<0.001), suggesting that the soft gel formulation has a better bioavailability than a dry-powder formulation.

References

Mar 29, 2000·Journal of Nutritional Science and Vitaminology·Y SuzukiT Kakuda

❮ Previous
Next ❯

Citations

Aug 10, 2011·Chinese Journal of Integrative Medicine·Pranav Kumar Prabhakar, Mukesh Doble
Jan 30, 2008·Evidence-based Complementary and Alternative Medicine : ECAM·Guy KleinXiaozhuo Chen
Oct 20, 2012·Evidence-based Complementary and Alternative Medicine : ECAM·Toshihiro MiuraTorao Ishida
Apr 2, 2008·Biological & Pharmaceutical Bulletin·Kotaro YamadaNobuya Inagaki
Apr 3, 2008·Journal of Basic and Clinical Physiology and Pharmacology·T T PriyaC I Jolly
Jul 19, 2008·Journal of Nutritional Science and Vitaminology·Satoshi TakagiTorao Ishida
Sep 15, 2011·Pakistan Journal of Biological Sciences : PJBS·N HaqueM Kamruzzaman
Jul 28, 2010·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Jing-Quan ZhengKuo-Cheng Lu
Jul 28, 2015·Phytochemistry Reviews : Proceedings of the Phytochemical Society of Europe·J Nazaruk, M Borzym-Kluczyk
Jun 10, 2006·Plant Physiology and Biochemistry : PPB·G PasquaB Botta
Mar 10, 2017·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Niege A J C FurtadoChristelle M André
Oct 13, 2017·European Journal of Nutrition·Jayapal Naveen, Vallikannan Baskaran
Jan 1, 2011·Nutrition and Metabolic Insights·Robert E CanaleRichard J Bloomer
Sep 2, 2016·Chemistry & Biodiversity·Guo-Qiang LiYao-Lan Li
Jul 13, 2006·Molecular Nutrition & Food Research·Benjamin RoffeyStan Kubow
Dec 25, 2008·Phytotherapy Research : PTR·Wenli HouYuquan Wei
Dec 1, 2009·Biotechnology Journal·Ganapathy SivakumarJackson O Lay
Jun 22, 2010·Phytotherapy Research : PTR·Chun-Ching ShihJin-Bin Wu
Aug 8, 2018·BMC Complementary and Alternative Medicine·Tasnuva SharminHabiba Mohammadi
Nov 19, 2011·Phytotherapy Research : PTR·Sidney J StohsGilbert R Kaats
Jul 28, 2010·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·N D YulianaR Verpoorte
Mar 19, 2020·Diabetes, Metabolic Syndrome and Obesity : Targets and Therapy·Giuseppe DerosaPamela Maffioli
May 1, 2021·Plants·Md Masudur RahmanJesus Simal-Gandara
May 1, 2021·International Journal of Molecular Sciences·Tovit Rosenzweig, Sanford R Sampson
Jan 8, 2008·Diabetes Research and Clinical Practice·Kotaro YamadaNobuya Inagaki
Nov 3, 2021·Journal of Medicinal Food·Luis D López-MurilloKarina G Pérez-Rubio

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

© 2022 Meta ULC. All rights reserved