Antidiabetic dimeric guianolides and a lignan glycoside from Lactuca indica

Journal of Natural Products
Chia-Chung HouFeng-Lin Hsu

Abstract

Three novel sesquiterpene lactones, lactucain A (1), B (2), and C (3), and a new furofuran lignan, lactucaside (4), were isolated from Lactuca indica along with nine known compounds, 11beta,13-dihydrolactucin, cichoriosides B, quercetin, quercetin 3-O-glucoside, rutin, apigenin, luteolin, luteolin 7-O-glucuronide, and chlorogenic acid. Among these compounds, latucain C (3) and lactucaside (4) showed significant antidiabetic activity.

References

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Citations

Jan 18, 2007·Archives of Pharmacal Research·Qing-He LiuEun-Rhan Woo
Oct 11, 2005·Archives of Pharmacal Research·Byung-Sun MinMee Ree Kim
Apr 6, 2005·Plant Cell Reports·J MalarzW Kisiel
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Dec 24, 2015·Journal of Natural Products·Chen ZhangPeng-Fei Tu
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Apr 19, 2011·Journal of Ethnopharmacology·Petra LüthjeAnnelie Brauner
May 17, 2018·Natural Product Research·Wen-Hui XuQian Liang
Oct 13, 2017·European Journal of Nutrition·Jayapal Naveen, Vallikannan Baskaran
Mar 2, 2018·Therapeutic Advances in Endocrinology and Metabolism·Sudhanshu Kumar BhartiAwanish Kumar
Jan 20, 2011·Natural Product Reports·Zha-Jun ZhanWei-Guang Shan
Oct 26, 2013·Tetrahedron Letters·Yulin RenA Douglas Kinghorn
May 15, 2020·Current Drug Metabolism·Deependra Singh ChauhanMohd Amir
Mar 8, 2008·Fitoterapia·Wanda Kisiel, Klaudia Michalska

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