Antidromic activation of a peptidergic pathway in the limbic system of the male rat

Brain Research
D AlbeckG J De Vries

Abstract

Stimulation of the medial amygdaloid nucleus (AME) produces a long-latency and long-lasting inhibition of pyramidal cells in both the dorsal and the ventral hippocampus. The inhibition is blocked by a specific antagonist to vasopressin, which is a candidate neurotransmitter in the system. Antidromic activation of the AME from the hippocampus occurs with a latency suggestive of the conduction velocity of small diameter unmyelinated fibers. Immunocytochemistry for vasopressin reveals small diameter, unmyelinated immunoreactive fibers in the vicinity of the stimulating electrode in the hippocampus, and immunoreactive cell bodies in the vicinity of the recording electrode in the AME.

References

Mar 1, 1979·Proceedings of the National Academy of Sciences of the United States of America·Y N JanS W Kuffler
Dec 11, 1992·Brain Research·T SmockH Weatherly
Jul 1, 1990·Journal of Neurobiology·G J De Vries, H A al-Shamma
Feb 1, 1989·Journal of Medicinal Chemistry·M ManningW H Sawyer
Jul 8, 1987·The Journal of Comparative Neurology·A R CafféP G Luiten
Mar 8, 1985·The Journal of Comparative Neurology·G J DeVriesD F Swaab
Sep 21, 1984·Science·R H SchellerR Taussig

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Citations

Nov 23, 2012·The Journal of Comparative Neurology·Zhenzhong CuiW Scott Young
Feb 2, 2018·Experimental Brain Research·Amrita BenoySreedharan Sajikumar

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