Antiepiligrin (laminin 5) cicatricial pemphigoid complicated and exacerbated by herpes simplex virus type 2 infection

The Australasian Journal of Dermatology
T K GilmourP M Todd

Abstract

A 50-year-old man with antiepiligrin (laminin 5) cicatricial pemphigoid (AeCP) involving the eyes, mouth and skin required a combination of systemic drug therapies to suppress the ocular disease. Herpes simplex virus type 2 infection of the mouth and pharynx precipitated an acute deterioration, with laryngeal involvement and an increase in oral ulceration. This is an unusual complication of long-term immunosuppression and illustrates some of the difficulties in the management of patients with AeCP. Clinical improvement was obtained with oral antiviral therapy and adjustment of his immunosuppressive regimen.

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Citations

May 12, 2007·Histochemistry and Cell Biology·Berit ByströmFatima Pedrosa Domellöf
Oct 1, 2013·Investigative Ophthalmology & Visual Science·André A M TorricelliSteven E Wilson
Jan 17, 2008·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·Paolo G Arduino, Stephen R Porter
Jan 9, 2010·The Laryngoscope·Thomas S HigginsJohn T Sinacori

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