Antifungal antibiotics and breakthrough bacteremias

Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America
R P WenzelM B Edmond

Abstract

Patients with fever and neutropenia are at high risk for infection ( approximately 50%) and bacteremia ( approximately 20%). As a result, most are treated with antibacterial prophylaxis until their absolute neutrophil count exceeds 500 cells/mm(3) and their temperature returns to normal. The 1997 guidelines of the Infectious Diseases Society of America suggested 1 of 3 regimens: vancomycin plus ceftazidime, monotherapy with ceftazidime or imipenem (possibly cefepime or meropenem), or dual therapy with an aminoglycoside plus an antipseudomonal beta-lactam.

References

Oct 6, 1997·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·W T HughesL S Young
Sep 7, 1999·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·M B EdmondR P Wenzel
Apr 19, 2000·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·W E Dismukes
May 8, 2001·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·C ViscoliUNKNOWN International Antimicrobial Therapy Cooperative Group of the European Organization for Research and Treatment of Cancer

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Citations

Dec 12, 2001·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Claudio ViscoliUNKNOWN International Antimicrobial Therapy Cooperative Group of the European Organization for Research and Treatment of Cancer

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Aminoglycosides (ASM)

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