Antigen-specific T-cell factors

Immunology
M J Taussig

Abstract

Antigen-specific T-cell factors are mediator molecules which are produced by helper and suppressor T cells and which can perform the function of those cells in an antigen-specific manner. They probably play an important part in immunoregulation. The major histocompatibility complex has a controlling influence on their structure and activity, while their antigen-recognition properties may be conferred by immunoglobulin V regions. Interest in the factors derives from three related areas of research, namely (i) the problem of T-cell recognition of antigen; (ii) the mechanisms of cellular interactions in antibody production and cell-mediated immunity; and (iii) the genetic control of immune responses. This review discusses the literature up to June 1980 on their production, structure, genetic restriction and mechanism of action.

References

Apr 1, 1976·European Journal of Immunology·S Kontiainen, M Feldmann
Oct 1, 1977·Proceedings of the National Academy of Sciences of the United States of America·J T NepomK E Hellström
Jan 1, 1978·Immunological Reviews·B Benacerraf, R N Germain
Jan 1, 1978·The Journal of Experimental Medicine·M P CancroN R Klinman
Dec 1, 1978·The Journal of Immunology : Official Journal of the American Association of Immunologists·L L PerryM I Greene
Jan 1, 1979·Immunological Reviews·R S Geha
Jan 1, 1979·Immunological Reviews·R E BallieuxB J Zegers
Jul 1, 1979·European Journal of Immunology·R R BernabeA Coutinho
Jan 1, 1979·Annals of the New York Academy of Sciences·M J TaussigA Holliman
Jan 1, 1979·Annals of the New York Academy of Sciences·A ReesN Zvaifler
Jan 1, 1979·Annals of the New York Academy of Sciences·M FeldmannJ N Woody
Mar 1, 1979·The Journal of Experimental Medicine·P Marrack, J W Kappler
Jul 14, 1977·Nature·S Gillis, K A Smith
Jan 1, 1979·Annals of the New York Academy of Sciences·E A Petersen, C H Kirkpatrick
Mar 1, 1977·The Journal of Experimental Medicine·J S McDougal, D S Gordon
Jan 1, 1977·Cold Spring Harbor Symposia on Quantitative Biology·T TadaC S David
Nov 1, 1977·The Journal of Experimental Medicine·M Taniguchi, J F Miller
Aug 3, 1978·Nature·S KontiainenM Feldmann
Aug 1, 1978·The Journal of Experimental Medicine·W PtakR K Gershon

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Citations

Jun 1, 1982·Veterinary Parasitology·L C Gasbarre, J F Urban
Sep 1, 1981·The Journal of Experimental Medicine·P LonaiG J Hämmerling
Feb 1, 1982·The Journal of Experimental Medicine·A F Clark, J D Capra
Aug 1, 1986·Kidney International·E G NeilsonR Mann
Feb 1, 1985·The Journal of Dermatology·K Kitamura
Mar 1, 1986·Scandinavian Journal of Immunology·A G WangelJ Koistinen
Sep 30, 1982·Journal of Immunological Methods·C L Reading

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