PMID: 107503Dec 1, 1978

Antigenic analysis of sequential erythrocytic stages of Plasmodium knowlesi

Parasitology
J A DeansS Cohen

Abstract

The antigenic composition of sequential erythrocytic stages of Plasmodium knowlesi has been compared by crossed immuno-electrophoresis using a pool of immune rhesus monkey antiserum. Eleven major parasite antigens have been identified; 9 are stage-independent, and 2 stage-dependent. Differences in the relative amount of the stage-independent antigens have been demonstrated and quantified. The distribution of antigens between parasites and schizont and infected red cell membranes has been examined. Only 6 of the 11 parasite antigens were exhibited by a schizont membrane preparation, all these antigens were also expressed by the intracellular parasite. Antigens exclusive to the schizont membrane were not demonstrated.

References

Sep 1, 1975·Proceedings of the National Academy of Sciences of the United States of America·P Owen, M R Salton
Mar 1, 1974·Journal of Immunological Methods·B M WrightV E Jones
Jan 1, 1963·Archives of Biochemistry and Biophysics·J T DODGED J HANAHAN

Citations

May 1, 1983·Molecular and Biochemical Parasitology·D C KaushalF M McAuliffe
Sep 1, 1979·Proceedings of the National Academy of Sciences of the United States of America·A Kilejian
Jun 1, 1980·Proceedings of the National Academy of Sciences of the United States of America·A Kilejian
Jul 1, 1983·The Journal of Experimental Medicine·R Schmidt-UllrichM T Monroe
Oct 1, 1981·British Journal of Hospital Medicine·C J Ellis
Jul 1, 1986·Molecular and Biochemical Parasitology·R Schmidt-UllrichM T Monroe
Apr 1, 1984·Molecular and Biochemical Parasitology·C I Newbold
Jan 1, 1984·Zeitschrift Für Parasitenkunde·J CarlssonP Perlmann
May 1, 1981·The Journal of protozoology·J G JohnsonL H Miller
Jan 15, 1979·Proceedings of the Royal Society of London. Series B, Containing Papers of a Biological Character·S Cohen
Jan 1, 1982·Immunological Reviews·R J Howard
Apr 1, 1987·Immunological Investigations·N A KaushalS Ghatak

Related Concepts

Anthropoidea
Antigens
Erythrocytes
Immunoelectrophoresis, Two-Dimensional
Macaca mulatta
Malaria
Plasmodium

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