PMID: 41423Jun 1, 1979

Antigenicity testing of plain and aluminium hydroxide-adsorbed whole-cell cholera vaccines

Acta Tropica
I Joó

Abstract

The antigenicity of a plain and of an aluminium hydroxide-adsorbed whole-cell cholera vaccine was investigated by the active mouse protection test and the vibriocidal antibody production assay in mice. In the active mouse protection test, between the antigenicity of the Inaba and Ogawa component of the two vaccines was no significant difference. The antibody production test, however, revealed that the adsorbed vaccine elicited higher and longer lasting immune response than the plain one. The antibody response to a two-dose immunization schedule was substantially superior to that after a one-dose schedule.

Related Concepts

Immune Response
Variolation
Immunologic Adjuvants
Vaccines
Alhydrogel
Antibody Formation
Antibody Studies (Procedure)
Antigens, Bacterial
Immunization Domain
Assay

Related Feeds

Avian Influenza: Innate Immune Adjuvant (ASM)

Adjuvants systems that are added to vaccines against avian influenza have be explored to enhance the innate immune system response against the virus. Here is the latest research on avian influenza and the innate immune adjuvant.

Avian Influenza: Innate Immune Adjuvant

Adjuvants systems that are added to vaccines against avian influenza have be explored to enhance the innate immune system response against the virus. Here is the latest research on avian influenza and the innate immune adjuvant.