Antihistone antibodies in scleroderma

Dermatology : International Journal for Clinical and Investigative Dermatology
A ParodiA Rebora

Abstract

Antihistone antibodies (AHA) are usually considered the serological marker of drug-induced lupus erythematosus, but recently they have been found in patients with systemic scleroderma (SSc) and morphea. We determined AHA in 43 patients with SSc, 4 patients with overlap syndrome and 11 with morphea. AHA were demonstrated in 41.8% of the SSc patients and in 36.3% of the morphea patients. Only 1 patient with overlap syndrome had AHA. Our SSc patients with AHA had frequent cardiac and renal involvements suggesting a prognostic value of AHA. In our morphea patients AHA did not correlate with clinical features.

Citations

Nov 3, 1998·Annals of the Rheumatic Diseases·M HasegawaK Takehara
Jan 16, 2014·The American Journal of Dermatopathology·Angel Fernandez-FloresMarcela Saeb-Lima
Aug 21, 2013·Actas dermo-sifiliográficas·I Bielsa Marsol
Jun 5, 2007·Seminars in Cutaneous Medicine and Surgery·Isabel Bielsa, Aurelio Ariza
Dec 21, 2004·The British Journal of Dermatology·S SatoK Takehara
Nov 2, 2006·International Journal of Dermatology·Rokea A el-AzharyHenry A Homburger
Feb 13, 2015·Anais Brasileiros De Dermatologia·Mariana Figueiroa Careta, Ricardo Romiti
Sep 13, 2002·Journal of the European Academy of Dermatology and Venereology : JEADV·L Orozco-CovarrubiasR Ruiz-Maldonado
Apr 25, 2018·The Journal of Dermatology·Yoshihide AsanoHironobu Ihn
May 8, 2018·European Journal of Pediatrics·Tamás ConstantinKathryn S Torok

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiomyopathy

Cardiomyopathy is a disease of the heart muscle, that can lead to muscular or electrical dysfunction of the heart. It is often an irreversible disease that is associated with a poor prognosis. There are different causes and classifications of cardiomyopathies. Here are the latest discoveries pertaining to this disease.

© 2021 Meta ULC. All rights reserved