PMID: 2507028Aug 19, 1989Paper

Antihypertensive effect of diet compared with drug treatment in obese men with mild hypertension

BMJ : British Medical Journal
A BerglundB Fagerberg

Abstract

To determine whether dietary treatment has a similar antihypertensive effect to conventional drug treatment while being superior to drugs in improving serum lipid concentrations in obese men with mild hypertension. Six week run in period followed by randomisation to either diet or drug treatment groups for one year. Outpatient clinic in city hospital. 61 Men aged 40-69 years, body mass index greater than or equal to 26, diastolic blood pressure 90-104 mm Hg when untreated. Exclusion criteria were signs of organ damage secondary to hypertension and diseases that might have interfered with compliance or with interpretation of results. Dietary treatment was based on weight reduction, restriction of sodium, and decrease of excess alcohol intake (defined as greater than or equal to 250 g alcohol per week). Drug treatment used a stepped care approach with atenolol as drug of first choice. Diastolic blood pressure less than 90 mm Hg; absolute reductions in blood pressure and serum lipid concentrations. Mean body weight decreased 7.6 kg in the diet group and increased 0.9 kg in the drug treatment group (p less than 0.0001), and mean sodium excretion decreased 42 and 10 mmol/24 h respectively (p = 0.019). There was no difference in repo...Continue Reading

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Citations

Oct 14, 2004·Journal of Hypertension·Donald J NicolsonJames M Mason
Oct 10, 2008·The Cochrane Database of Systematic Reviews·Cynthia D MulrowM Brand
May 2, 2013·The Cochrane Database of Systematic Reviews·Feng J HeGraham A Macgregor
Feb 20, 2004·The Cochrane Database of Systematic Reviews·L HooperS Ebrahim
Jul 2, 2020·The Cochrane Database of Systematic Reviews·Sara TasnimJames M Wright
Apr 25, 2000·American Journal of Hypertension·I Ben-DovM Gaides

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