Antihypertensive treatment and sexual dysfunction.

Current Hypertension Reports
Athanasios Manolis, Michael Doumas

Abstract

Sexual dysfunction is frequently encountered in hypertensive patients. Available data indicates that sexual dysfunction is more frequent in treated than in untreated patients, generating the hypothesis that antihypertensive therapy might be associated with sexual dysfunction. Several lines of evidence suggest that differences between antihypertensive drugs exist regarding their effects on sexual function. Older antihypertensive drugs (diuretics, beta blockers) exert detrimental effects on erectile function whereas newer drugs (nebivolol, angiotensin receptor blockers) have neutral or even beneficial effects. Phosphodiesterase (PDE)-5 inhibitors are effective in hypertensive patients and can be safely administered even when multidrug regimes are used. Precautions need to be taken with alpha blockers or patients with uncontrolled high-risk hypertension, while co-administration with nitrates is contraindicated.

References

Apr 15, 1991·Annals of Internal Medicine·S Wassertheil-SmollerH G Langford
Dec 1, 1987·Journal of Hypertension. Supplement : Official Journal of the International Society of Hypertension·R F BingJ D Swales
Nov 3, 1998·American Journal of Hypertension·R FogariP Lusardi
Mar 17, 1999·The American Journal of Cardiology·G JacksonM J Allen
Jul 29, 2000·European Journal of Endocrinology·M MaggiG Forti
Feb 24, 2001·American Journal of Hypertension·R FogariL Corradi
May 24, 2001·The American Journal of the Medical Sciences·J L LlisterriC M Ferrario
Jul 11, 2002·European Journal of Clinical Pharmacology·Roberto FogariAmedeo Mugellini
Jul 16, 2002·JAMA : the Journal of the American Medical Association·Dennis T KoHarlan M Krumholz
Jul 23, 2003·Journal of Human Hypertension·A Della ChiesaO M Hess
Aug 9, 2003·International Journal of Impotence Research·A J BecharaJ E Toblli
Nov 12, 2003·The American Journal of Cardiology·Robert A KlonerJeffrey T Emmick
Jan 1, 2004·American Journal of Hypertension·Roberto FogariAmedeo Mugellini
Apr 23, 2004·International Journal of Impotence Research·J E ToblliF Inserra
Jun 5, 2004·American Journal of Hypertension·JorgeEduardo ToblliFelipe Inserra
Jun 24, 2004·JAMA : the Journal of the American Medical Association·Katherine EspositoDario Giugliano
Jan 18, 2005·Lancet·Patricia M KearneyJiang He
Jun 11, 2005·The Journal of Urology·Drogo K MontagueUNKNOWN Erectile Dysfunction Guideline Update Panel
Jul 16, 2005·The American Journal of Cardiology·John B KostisRidwan Shabsigh
Jan 6, 2006·International Journal of Impotence Research·K EspositoD Giugliano
Apr 6, 2006·The Journal of Clinical Hypertension·Michael Doumas, Stella Douma
May 12, 2006·The Journal of Clinical Hypertension·Michael Doumas, Stella Douma
Nov 4, 2006·Journal of Hypertension·Michael DoumasHelen Giamarellou
Dec 13, 2006·American Journal of Hypertension·Jorge Eduardo ToblliOsvaldo Néstor Mazza
Jul 31, 2007·The American Journal of Cardiology·Richard E ScrantonJ Michael Gaziano
Aug 4, 2007·International Journal of Impotence Research·K EspositoD Giugliano
Jul 4, 2008·International Journal of Impotence Research·M BaumhäkelUNKNOWN DO-IT Investigators
Oct 16, 2008·Journal of Hypertension·Athanasios Manolis, Michael Doumas
Jan 28, 2009·The Journal of Sexual Medicine·Johanna L HannanMichael A Adams
Feb 3, 2009·Journal of the American College of Surgeons·Ramsey M DallalBrian B Quebbemann
Mar 24, 2009·The Journal of Clinical Hypertension·Sikiru LaminaTheophilus T Dagogo
Jan 16, 2010·Cardiovascular Therapeutics·Alberto CorderoJosé Ramón González-Juanatey
Dec 24, 2010·Journal of Hypertension·Margus ViigimaaUNKNOWN European Society of Hypertension Working Group on Sexual Dysfunction

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Citations

Jun 12, 2013·Current Hypertension Reports·Michael DoumasPeter Kokkinos
Sep 28, 2013·Netherlands Heart Journal : Monthly Journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation·M P J NicolaiH W Elzevier
Apr 26, 2013·European Heart Journal·Charalambos VlachopoulosPiero Montorsi
Oct 25, 2013·Netherlands Heart Journal : Monthly Journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation·M P J NicolaiH W Elzevier
Dec 18, 2013·Pharmacology, Biochemistry, and Behavior·Heiko GrafBirgit Abler
Sep 30, 2015·Clinical and Experimental Hypertension : CHE·Nathan ArtomAldo Pende
Oct 21, 2015·Internal Medicine Journal·Rafael RamirezUNKNOWN Xarxa de Unitats de Lípids i Arteriosclerosi (XULA) Investigators Group
Jul 9, 2013·Progrès en urologie : journal de l'Association française d'urologie et de la Société française d'urologie·F Giuliano, S Droupy
Jun 5, 2013·The Journal of Clinical Hypertension·Jane HarmanSharon B Wyatt
Jan 9, 2013·Current Opinion in Pharmacology·Paul M Vanhoutte, Yuansheng Gao
Jan 21, 2014·American Heart Journal·Melianthe P J NicolaiHenk W Elzevier
May 3, 2016·International Braz J Urol : Official Journal of the Brazilian Society of Urology·Weslley Santiago AndradeJose Augusto Soares Barreto-Filho
Jun 18, 2017·Andrology·M SemetJ Perrin
Feb 26, 2016·Journal of Cardiovascular Medicine·Christian CadedduUNKNOWN Working Group of Gender Medicine of Italian Society of Cardiology
Mar 19, 2019·Journal of Hypertension·Aruna V SarmaUNKNOWN DCCT/EDIC Research Group
Jun 17, 2020·Andrologia·Ayodeji Folorunsho Ajayi, Roland Eghoghosoa Akhigbe
Nov 28, 2013·Journal of Cardiovascular Pharmacology and Therapeutics·Nikolaos Ioakeimidis, John B Kostis
Feb 21, 2019·JAMA Surgery·Kristine J SteffenAlison J Huang
Jul 7, 2020·Liver International : Official Journal of the International Association for the Study of the Liver·Frank E UschnerSabine Klein
Sep 1, 2013·Arab Journal of Urology·Andrea SaloniaFrancesco Montorsi
Aug 29, 2017·The Aging Male : the Official Journal of the International Society for the Study of the Aging Male·Kadir Uğur MertAta Özen
Nov 18, 2018·The Aging Male : the Official Journal of the International Society for the Study of the Aging Male·Onder Canguven
Mar 15, 2020·Current Hypertension Reports·Peter M NilssonRenata Cifkova
Feb 26, 2019·Journal of Human Hypertension·Ozlem CeyhanAydan Dogan
Nov 13, 2014·The Medical Journal of Australia·Alistair Vickery, Peter L Thompson
Dec 15, 2020·The Journal of Clinical Hypertension·Tzung-Dau WangUNKNOWN HOPE Asia Network
Jul 23, 2020·European Journal of Internal Medicine·Athanasios ManolisGiuseppe Mancia
Apr 15, 2020·Current Vascular Pharmacology·Konstantinos ImprialosMichael Doumas

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