PMID: 11902644Mar 21, 2002Paper

Antimicrobial activity of 5-arylidene aromatic derivatives of hydantoin. Part 2

Il Farmaco
Ewa SzymańskaAndrzej Kasprowicz

Abstract

Various 5-chloroarylidene-2-amino substituted derivatives of imidazoline-4-one were synthesized and evaluated for their activity in vitro against Mycobacterium tuberculosis and other type strains of bacteria and fungi. 2-Chloro- and 2,4-dichlorobenzylidene substituted hydantoins exhibited antimycobacterial effect. The most potent compounds 3i, 3j, 3o, 3q and 3s were classified for further tests. The antimitotic effect of the investigated hydantoins was also examined.

References

Dec 18, 2002·Il Farmaco·K Kieć-Kononowicz, E Szymańska

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Citations

Dec 18, 2002·Il Farmaco·K Kieć-Kononowicz, E Szymańska
Jun 16, 2011·ACS Combinatorial Science·Guillermo Gerona-NavarroMiriam Royo
Feb 17, 2009·Nature Chemical Biology·Kristen M GarnerAlan Eastman
May 10, 2011·FEBS Letters·Jean-Michel BollaJean-Marie Pagès
Oct 18, 2011·European Journal of Medicinal Chemistry·Jadwiga HandzlikSandrine Alibert
Jul 3, 2010·Bioorganic & Medicinal Chemistry·Ivanna Subtel'naRoman Lesyk
Nov 28, 2012·International Journal of Biological Macromolecules·Nagy M KhalifaMogedda E Haiba
Jun 15, 2013·International Journal of Molecular Sciences·Jintao HanMingan Wang
Nov 17, 2007·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Jean-René ChérouvrierJean Pierre Bazureau
Feb 13, 2007·Bioorganic & Medicinal Chemistry·Yves L Janin
Oct 7, 2017·Journal of Medicinal Chemistry·Ma SuJianfeng Cai
Sep 12, 2020·Journal of Medicinal Chemistry·Minghui WangJianfeng Cai

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