Antimicrobial activity of coffee melanoidins-a study of their metal-chelating properties

Journal of Agricultural and Food Chemistry
José A Rufián-Henares, Silvia P de la Cueva

Abstract

Melanoidins comprise a substantial proportion of severely heat-treated foods such as baked cereals or roasted coffee and are widely consumed dietary components. The antimicrobial activity of coffee melanoidins against different pathogenic bacteria has been studied, finding that such activity is due to their metal-chelating properties. Three different mechanisms have been observed: at low concentrations melanoidins exerted a bacteriostatic activity mediated by iron chelation from the culture medium; in the case of bacterial strains that are able to produce siderophores for iron acquisition, melanoidins chelate the siderophore-Fe3+ complex, which could decrease the virulence of such pathogenic bacteria; and, finally, coffee melanoidins also exerted a bactericide activity at high concentrations by removing Mg2+ cations from the outer membrane, promoting the disruption of the cell membrane and allowing the release of intracellular molecules.

References

May 1, 1989·International Journal of Food Microbiology·M Tiina, M Sandholm
Jan 1, 1987·Analytical Biochemistry·B Schwyn, J B Neilands
Dec 24, 1998·Journal of Pharmaceutical and Biomedical Analysis·M DagliaG Gazzani
Oct 6, 2000·Annual Review of Microbiology·C Ratledge, L G Dover
Jul 9, 2002·Biomaterials·Chris Zhisheng Chen, Stuart L Cooper
May 10, 2003·The Science of the Total Environment·Carmen CabreraM Carmen López
Mar 3, 2005·Journal of Agricultural and Food Chemistry·Cristina Delgado-Andrade, Francisco J Morales
Mar 31, 2005·Journal of Agricultural and Food Chemistry·Xu WenSeiichi Homma
Sep 30, 2005·Journal of Agricultural and Food Chemistry·Cristina Delgado-AndradeFrancisco J Morales
Aug 31, 2006·Journal of Agricultural and Food Chemistry·Jae-Young Je, Se-Kwon Kim
Jan 25, 2007·Journal of Agricultural and Food Chemistry·José A Rufian-Henares, Francisco J Morales
Feb 1, 2007·Journal of Agricultural and Food Chemistry·E Koen BekedamGerrit Smit
Apr 26, 2007·Journal of Agricultural and Food Chemistry·Fernando M Nunes, Manuel A Coimbra
Sep 7, 2007·Microbiology and Molecular Biology Reviews : MMBR·Marcus Miethke, Mohamed A Marahiel
Oct 31, 2007·Journal of Agricultural and Food Chemistry·José A Rufián-Henares, Francisco J Morales
Mar 15, 2008·Journal of Agricultural and Food Chemistry·Jose A Rurián-Henares, Francisco J Morales

❮ Previous
Next ❯

Citations

Oct 16, 2010·Amino Acids·Francisco J MoralesVincenzo Fogliano
Jul 23, 2011·Food & Function·Ulla MuellerMonika Pischetsrieder
Jul 13, 2011·Annals of Family Medicine·Eric M MathesonDana E King
Jan 1, 2013·International Journal of Food Science·John Yew Huat TangChe Abdullah Abu Bakar
Jul 6, 2014·Food Chemistry·Silvia Pastoriza, José A Rufián-Henares
Aug 21, 2010·Molecular Nutrition & Food Research·Martinus van BoekelGerhard Eisenbrand
May 29, 2014·Molecular Nutrition & Food Research·Isabel SeiquerMaría Pilar Navarro
Apr 5, 2014·Journal of the Science of Food and Agriculture·Xu HongRong-Rong Lu
Nov 26, 2015·Food Chemistry·Mariela PatrignaniCecilia Elena Lupano
Mar 24, 2015·Environmental Technology·Milton M ArimiSven-Uwe Geißen
May 27, 2015·European Journal of Nutrition·Cristina Delgado-AndradeMaría Pilar Navarro
Oct 17, 2013·Food Chemistry·Carolin HauserMonika Pischetsrieder
Apr 7, 2015·Food Chemistry·Ewelina StelmachAnna Szymczycha-Madeja
Feb 21, 2013·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Maria G MiguelAna R Silvério
Jun 23, 2016·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Ru SongGuanqiang Ruan
Jan 11, 2017·Journal of the Science of Food and Agriculture·Blanca A Mondaca-NavarroRoberto Rodríguez-Ramírez
Jan 20, 2018·Annual Review of Food Science and Technology·Cristina Delgado-Andrade, Vincenzo Fogliano
Jun 6, 2019·Food & Function·G L HuM H Qiu
May 16, 2012·Food & Function·Ana S P MoreiraManuel A Coimbra
May 29, 2013·Food & Function·Mariana D ArgirovaAthanas D Krustev
Mar 29, 2014·Food & Function·Iziar A LudwigAlan Crozier
Nov 19, 2019·Critical Reviews in Food Science and Nutrition·Yu FuRotimi E Aluko
Jul 6, 2014·Journal of Food Protection·Maxine J RomanJulie M Goddard
Jul 12, 2019·Environmental Science and Pollution Research International·Nahla A El-WakilSoheir S Abd El-Salam
Aug 14, 2019·Journal of Oral Science·Koji OgataYoshihisa Yamashita
May 7, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Luigi CastaldoAlberto Ritieni
Dec 7, 2019·Food Science and Biotechnology·Majid NooshkamSeyed Ali Mortazavi
Jun 20, 2020·Critical Reviews in Food Science and Nutrition·Raffaella Colombo, Adele Papetti
May 5, 2017·Environmental Science and Pollution Research International·Hamady DiengGabriel Tonga Noweg
Apr 29, 2018·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Brandilyn A PetersJiyoung Ahn
Nov 1, 2016·Comprehensive Reviews in Food Science and Food Safety·Hengye ChenFusheng Chen
Nov 18, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Ewa OlechnoKatarzyna Socha
Dec 19, 2020·Comprehensive Reviews in Food Science and Food Safety·Moting LiFuguo Liu

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Journal of Agricultural and Food Chemistry
José A Rufián-Henares, Francisco J Morales
Journal of Agricultural and Food Chemistry
Jose A Rurián-Henares, Francisco J Morales
Molecular Nutrition & Food Research
Rose C Borrelli, Vincenzo Fogliano
© 2021 Meta ULC. All rights reserved