Antimicrobial activity of confertifolin from Polygonum hydropiper

Pharmaceutical Biology
V DuraipandiyanS Ignacimuthu

Abstract

Confertifolin (6,6,9a-trimethyl-4,5,5a,6,7,8,9,9a-octahydronaphtho[1,2-c] furan-3 (1H)-one) was isolated from the essential oil of Polygonum hydropiper L. (Polygonaceae) leaves using column chromatography. Confertifolin showed activity both in bacteria and fungi. The lowest MIC for bacteria was observed against Enterococcus faecalis (31.25 microg/mL). Significant MIC for fungi was observed against Scopulariopsis sp (7.81 microg/mL), Curvularia lunata (7.81 microg/mL), Epidermophyton floccosum (7.81 microg/mL), Trichophyton mentagrophytes (16.62 microg/mL), Trichophyton rubrum (MTCC 296) (16.62 microg/mL), Aspergillus niger (31.25 microg/mL), Botrytis cinerea (31.25 microg/mL) Magnaporthe grisea (62.5 microg/mL), Trichophyton simii (125 microg/mL) and Trichophyton rubrum (clinical isolate) (125 microg/mL).

References

Jun 1, 1997·Journal of Applied Microbiology·M Lis-Balchin, S G Deans
Aug 7, 1999·Journal of Applied Microbiology·K A HammerT V Riley
Sep 20, 2001·Memórias do Instituto Oswaldo Cruz·T M de Almeida AlvesC L Zani
Dec 17, 2002·Phytochemistry·Zhao Feng PengLian Sai Chia
Dec 20, 2002·Fitoterapia·Eva RahmanM Ahmed
May 29, 2007·Journal of Ethnopharmacology·V Duraipandiyan, S Ignacimuthu

❮ Previous
Next ❯

Citations

May 17, 2014·Evidence-based Complementary and Alternative Medicine : ECAM·A K M Moyeenul HuqJohnson Stanslas
Apr 20, 2014·Journal of Ethnopharmacology·Alexander N ShikovMichael Heinrich
Jul 18, 2018·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Annabelle St-PierreIsabel Desgagné-Penix
Jul 13, 2021·Frontiers in Endocrinology·Qin XiaTing Chen

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antifungals

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

Antifungals (ASM)

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.