Antimicrobial Activity of Extracts of the Oyster Culinary Medicinal Mushroom Pleurotus ostreatus (Higher Basidiomycetes) and Identification of a New Antimicrobial Compound

International Journal of Medicinal Mushrooms
Ahmed M YounisHussien H El Shikh

Abstract

Pleurotus ostreatus is an edible mushroom that also has high medicinal values. In this study, P. ostreatus was tested for its ability to inhibit the growth of fungi and bacteria. The freeze-dried fruiting body, broth from submerged culture, and mycelial biomass of P. ostreatus were extracted using alcohols and water as solvents. The extracts were then tested for their antimicrobial activity against the growth of fungi and bacteria. It was observed that the water extract from fruiting bodies had the strongest effect in inhibiting the growth of most fungi. The most sensitive test microfungi to the inhibition were Candida albicans, Cryptococcus humicola, and Trichosporon cutaneum, and the most sensitive test bacteria were Staphylococcus aureus followed by Escherichia coli. Water extracts from culture broth or mycelial biomass were moderately inhibitive to the growth of fungi and bacteria. The alcohol-based solvents from all samples had much less antimicrobial activity against most test microorganisms. An antimicrobial compound was purified from the water extracts of fruiting bodies with Sephadex G 100 column chromatography and characterized by infrared absorption spectrum (IR), nuclear magnetic resonance (NMR), and mass spectrosco...Continue Reading

Citations

Sep 5, 2019·Current Pharmaceutical Biotechnology·Ahmed M YounisMohamed Yosri
Dec 14, 2017·Evidence-based Complementary and Alternative Medicine : ECAM·Theresa AppiahChristian Agyare
May 1, 2021·Membranes·Maja GrundnerMatej Skočaj
Jun 11, 2021·Food & Function·Míria Benetati Delgado BertéliNelson Barros Colauto

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