Antimicrobial and Antibiofilm Activities of Sulfated Polysaccharides from Marine Algae against Dental Plaque Bacteria

Marine Drugs
Joon-Young JunByoung-Mok Kim

Abstract

Dental plaque biofilms cause various dental diseases; therefore, inhibiting the growths of the dental plaque bacteria which produce biofilms can be a strategy for preventing dental disease. Certain sulfated polysaccharides from marine algae exert antimicrobial activities against human bacterial pathogens in addition to their physiological benefits. On the basis of these observations, the antimicrobial and antibiofilm activities of sulfated polysaccharides from different marine algae were evaluated against dental plaque bacteria. Among the sulfated polysaccharides, a fucoidan from Fucus vesiculosus showed notable antimicrobial activities against the selected dental plaque bacteria, including some foodborne pathogenic bacteria. The minimum inhibitory concentrations were of 125 to 1000 µg mL-1. Regarding the antibiofilm activity, the fucoidan at the concentrations of above 250 µg mL-1 completely suppressed the biofilm formations and planktonic cell growths of Streptococcus mutans and S. sobrinus. However, no eliminative effect on the completed biofilm was observed. The fucoidan consisted of almost fucose base polysaccharide containing approximately 14.0% sulfate content. The average molecular weight of the fucoidan was changed by ...Continue Reading

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Citations

Oct 12, 2019·Marine Drugs·Helen J FittonSamuel N Karpiniec
Oct 14, 2019·Journal of Biomedical Materials Research. Part a·Eduardas CicinskasAlexandra A Kalitnik
Sep 26, 2020·Folia Microbiologica·Goutam MukherjeeAlok Kumar Sil
May 27, 2020·Applied Microbiology and Biotechnology·Jyoti Vishwakarma, Sirisha V L
Sep 20, 2019·Antioxidants·Andrea Gomez-ZavagliaJesus Simal-Gandara
Mar 25, 2021·International Journal of Biological Macromolecules·Yanli ZhuJing Deng
Apr 3, 2021·International Journal of Biological Macromolecules·Mengyao ZhangHua Zheng
May 1, 2021·Marine Drugs·Eduarda M CabralMarco Garcia-Vaquero
Aug 28, 2021·Applied Biochemistry and Biotechnology·Jyoti VishwakarmaSirisha L Vavilala
Sep 1, 2021·Critical Reviews in Food Science and Nutrition·Paz OteroM A Prieto
Dec 24, 2021·Journal of Basic Microbiology·Moupriya NagRina R Ray

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Software Mentioned

SPSS
Cirrus GPC

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