Antimicrobial and mercury resistance in aerobic gram-negative bacilli in fecal flora among persons with and without dental amalgam fillings.

Antimicrobial Agents and Chemotherapy
M OsterbladP Huovinen

Abstract

Antimicrobial resistance is more widespread than can be accounted for as being a consequence of the selection pressure caused by the use of antibiotics alone. In this study, we tested the hypothesis that a high mercury content in feces might select for mercury-resistant bacteria and thus for antimicrobial resistance linked to mercury resistance. Three subject groups with different exposures to dental amalgam fillings were compared. None of the subjects had taken antimicrobial agents during the three preceding months or longer. The group exposed to dental amalgam (n = 92) had 13 times more mercury in feces than the group that had never been exposed to amalgam (n = 43) and the group whose amalgam fillings had been removed (n = 56). No significant differences in either mercury resistance or antibiotic resistance in the fecal aerobic gram-negative flora of these subject groups were seen. The following antimicrobial resistance frequencies were detected with a replica plating method: > or = 1% resistance was seen in 40% of the subjects for ampicillin, 14% of the subjects for cefuroxime, 6% of the subjects for nalidixic acid, 14% of the subjects for trimethoprim, 19% of the subjects for sulfamethoxazole, and 25% of the subjects for te...Continue Reading

References

Apr 1, 1992·The Journal of Antimicrobial Chemotherapy·S G AmyesH K Young
Aug 1, 1990·Journal of Medical Microbiology·J S Grewal, R P Tiwari
Dec 1, 1988·Antimicrobial Agents and Chemotherapy·S B LevyJ Davis
Aug 1, 1985·Antimicrobial Agents and Chemotherapy·P HuovinenP Toivanen
Apr 1, 1969·British Journal of Industrial Medicine·L Magos, A A Cernik
Jul 1, 1982·Journal of Bacteriology·F de la Cruz, J Grinsted
Nov 1, 1983·Reviews of Infectious Diseases·J E McGowan
Nov 1, 1982·Antimicrobial Agents and Chemotherapy·F D PorterH Nakahara
Jun 1, 1993·Antimicrobial Agents and Chemotherapy·E HeikkiläP Huovinen
May 1, 1993·Applied and Environmental Microbiology·R E FarrellP M Huang
Mar 1, 1952·Journal of Bacteriology·J LEDERBERG, E M LEDERBERG
Dec 1, 1987·Applied and Environmental Microbiology·T Barkay
Sep 1, 1988·Applied and Environmental Microbiology·G S Wickham, R M Atlas

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Citations

Apr 23, 2003·Microbial Drug Resistance : MDR : Mechanisms, Epidemiology, and Disease·Rachel PikeMichael Wilson
Jun 1, 1999·The Journal of Antimicrobial Chemotherapy·M OsterbladP Huovinen
Sep 3, 1999·The Journal of Antimicrobial Chemotherapy·M OsterbladP Huovinen
May 19, 2000·Antimicrobial Agents and Chemotherapy·M OsterbladP Kotilainen
Jun 20, 2007·Scandinavian Journal of Infectious Diseases·Sofia D NybergJari Jalava
Oct 19, 2006·Expert Opinion on Drug Safety·Michael D Martin, James S Woods
Apr 2, 2002·Archives of Oral Biology·Keun Bae SongHo Keun Kwon
Mar 16, 2006·Trends in Microbiology·Craig Baker-AustinJ V McArthur
Jul 7, 2011·FEMS Microbiology Reviews·Mark A Toleman, Timothy R Walsh
May 1, 1997·Toxicology and Applied Pharmacology·L BjörkmanJ Ekstrand
May 11, 2007·FEMS Microbiology Letters·Rustam I Aminov, Roderick I Mackie
Sep 16, 2008·Archives of Oral Biology·H Nur OzdabakNilgün Seven
Feb 28, 2001·Environmental Microbiology·A AlonsoJ L Martínez
Jan 18, 2003·Archives of Environmental Health·Jorma LeistevuoJorma Tenovuo
Apr 29, 2009·Journal of Environmental Quality·Joanne C Chee-SanfordRustam I Aminov
Nov 15, 1997·Applied and Environmental Microbiology·J WiremanA O Summers

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