Antimicrobial and physicochemical properties of experimental light curing composites with alkali-substituted calcium phosphate fillers

Dental Materials : Official Publication of the Academy of Dental Materials
Wolf HerzliebU Gbureck

Abstract

The antimicrobial and physicochemical properties of experimental light curing composites prepared with fillers made of mechanically activated alkali-substituted calcium phosphates like CaKPO(4), CaNaPO(4) or Ca(2)KNa(PO(4))(2) were compared with a commercial silane-modified cristobalite filler. The antimicrobial properties were tested using Streptococcus mutans, Staphylococcus aureus and a clinically isolated plaque mixture. The potential for reducing bacteria growth on modified composites was determined using the proliferation reagent WST-1, which enables the measurement of metabolic activity and therefore the colonization with living bacteria. Investigated material properties included the degree of conversion and a test of flexural strength. All alkali-substituted composites provide a changed, mainly basic micro-milieu leading to a reduction of bacteria population with respect to the non-modified composite of about 25-70% with a flexural strength of cured composites in the range of 55-77 MPa complying with the clinical standard and a degree of conversion of 44-66%. This study suggests that the modified composites increase antimicrobial properties while basic composite characteristics are not influenced by the filler.

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Citations

Dec 19, 2016·Advanced Healthcare Materials·Laura WistlichJürgen Groll
Jul 23, 2016·Technology and Health Care : Official Journal of the European Society for Engineering and Medicine·Shahid AliNaresh Kumar
Oct 9, 2019·Technology and Health Care : Official Journal of the European Society for Engineering and Medicine·Shahid AliMuhammad S Zafar

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