PMID: 8596073Oct 1, 1995Paper

Antimicrobial and toxic effects of established and potential root canal irrigants

Journal of Endodontics
C YesilsoyM Trope

Abstract

Three dilutions of the commonly used irrigant sodium hypochlorite (0.5%, 2.5%, and 5.25%) and the potential irrigants Peridex, chlorhexidine gluconate (0.12%), and Therasol were tested. Alcohol and saline served as controls also. The in vitro portion of this study used four different microorganisms (Streptococcus mutans, Peptostreptococcus micros, Prevotella intermedius, and Porphyromonas gingivalis) to determine antimicrobial effect. Presterilized 7-mm diameter Whatman paper disks soaked with the test solution were prepared, and disks were placed onto the previously seeded agar petri dishes. Each dish was incubated aerobically or anaerobically according to the microorganisms used. An in vivo animal model (guinea pig) was used to examine subcutaneous local tissue reactions using the same materials; 0.1 ml of each test solution was injected subcutaneously into predetermined locations on the animal dorsum. Test site histological examination was done 2 h, 2 days, and 2 wk after the injections. The results of this comparative study indicate Peridex (chlorhexidine gluconate) and Therasol may have good potential for endodontic usage.

Citations

Feb 24, 2001·Journal of Endodontics·F TaşmanI Etikan
Jun 13, 2003·International Endodontic Journal·O OnçağD Burhanoğlu
Feb 25, 2003·Journal of Endodontics·David B FergusonGary R Hartwell
May 27, 2005·Journal of Endodontics·Katherine R CarsonScott B McClanahan
Sep 30, 2005·Acta Odontologica Scandinavica·Till DammaschkeEdgar Schäfer
Jan 18, 2006·International Endodontic Journal·T LambrianidisM Mazinis
Dec 18, 2008·Journal of Applied Oral Science : Revista FOB·João Eduardo Gomes-FilhoPedro Felício Estrada Bernabé
Oct 1, 2007·Journal of Applied Oral Science : Revista FOB·Bruno Carvalho de VasconcelosEduardo Diogo Gurgel-Filho
Oct 22, 2010·The International Journal of Artificial Organs·Claudio PoggioLivia Visai
Jul 21, 2011·Australian Endodontic Journal : the Journal of the Australian Society of Endodontology Inc·Vivek AggarwalDebipada Kabi
Apr 14, 2012·British Dental Journal·J Prichard
Nov 19, 2011·The International Journal of Artificial Organs·Claudio PoggioLivia Visai
May 4, 2013·Acta Odontologica Scandinavica·Arindam Dutta, Mala Kundabala
May 4, 2018·Brazilian Oral Research·Carlos Augusto de Morais Souto PantojaJosé Flávio Affonso de Almeida
Nov 27, 2002·International Endodontic Journal·M Tanomaru FilhoL H Faccioli
Apr 2, 2004·International Endodontic Journal·C R GernhardtM Brandt
Sep 1, 2005·Australian Endodontic Journal : the Journal of the Australian Society of Endodontology Inc·Bettina Basrani, Carlie Lemonie
Jul 26, 2006·British Dental Journal·S J BonsorG J Pearson
Dec 25, 2010·Srpski arhiv za celokupno lekarstvo·Violeta Pavlović, Slavoljub Zivković
Nov 5, 2011·Dental Traumatology : Official Publication of International Association for Dental Traumatology·Claudio PoggioStefano Bianchi
Dec 20, 2013·Journal of Oral Science·Seyedmohsen HasheminiaMorteza Rajabzadeh
Oct 21, 2016·Journal of Functional Biomaterials·Alberto DagnaClaudio Poggio
Aug 24, 2002·International Endodontic Journal·J T Marais, W P Williams
Sep 11, 2003·Brazilian Dental Journal·Luciana Moura SassoneRaphael Júnior Hirata
Mar 27, 2007·Brazilian Oral Research·Juliane Maria Guerreiro TanomaruIzabel Yoko Ito
Aug 14, 2008·International Endodontic Journal·P SurapipongpuntrA Ekka
Mar 21, 2008·Australian Endodontic Journal : the Journal of the Australian Society of Endodontology Inc·Luciana M SassoneRafael Hirata
Dec 12, 2012·Microscopy Research and Technique·Maíra Do PradoBrenda P F A Gomes
Jun 18, 1999·International Endodontic Journal·H AyhanH Bodur
Jun 13, 2003·International Endodontic Journal·J C YamashitaL A B Silva
Dec 4, 2003·International Endodontic Journal·J M G TanomaruL A B Silva

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