Antimicrobial and Wound Healing Properties of Polyacrylonitrile-Moringa Extract Nanofibers

ACS Omega
Omolola Esther FayemiEno E Ebenso

Abstract

A simple and cost-effective material composed of polyacrylonitrile nanofibers containing different concentrations of moringa (MR) leaf extracts was fabricated for antimicrobial properties and wound dressing. The fabricated materials were characterized by scanning electron microscopy, thermal gravimetric analysis, and Fourier transmission infrared spectroscopy. The antibacterial sensitivity of the developed polyacrylonitrile-moringa extract nanofibers was evaluated against Staphylococcus aureus and Escherichia coli by the agar diffusion method. A pronounced antibacterial activity was observed with the increase in the incorporated moringa leaf extract concentration within the polyacrylonitrile-moringa extract nanofibers against the bacterial strains. The best antibacterial sensitivity was observed for nanofibers containing 0.5 g of moringa leaf extract which had an inhibitory zone of 15 mm for E. coli and 12 mm for S. aureus. Furthermore, the cost-effective and biodegradable nanofibrous polyacrylonitrile-moringa extract nanofiber was also used to conduct further studies regarding wound dressing. The result reveals that the increase in the concentrations of moringa leaf extract influenced the healing properties of the material. Fo...Continue Reading

References

Feb 1, 1996·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·A Martin
Jul 21, 2004·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Dhirendra S KattiCato T Laurencin
May 12, 2005·Nano Letters·Dan LiYounan Xia
May 27, 2005·Applied Biochemistry and Biotechnology·J Venugopal, S Ramakrishna
Jul 1, 2005·Nursing·Rita A Frantz
Jul 26, 2005·Journal of Ethnopharmacology·P J HoughtonA M Deters
Sep 17, 2005·Journal of Materials Science. Materials in Medicine·Yanzhong ZhangZheng-Ming Huang
Feb 10, 2010·Pharmaceutical Research·Francis IgnatiousJohn Baldoni
Aug 28, 2010·Journal of Biomedicine & Biotechnology·T D J Heunis, L M T Dicks
Jan 26, 2011·Biotechnology Advances·R JayakumarH Tamura
Feb 5, 2011·ACS Applied Materials & Interfaces·Jingbo MuYichun Liu
Jan 1, 2010·Annual Review of Chemical and Biomolecular Engineering·William B LiechtyNicholas A Peppas
May 18, 2013·International Journal of Pharmaceutics·Natthan CharernsriwilaiwatPraneet Opanasopit
Jul 22, 2014·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Ashwell R NdhlalaJohannes Van Staden
Sep 3, 2014·Journal of Biomaterials Applications·R ManjumeenaR Venkatesan
Nov 26, 2015·The EPMA Journal·Ana C FonsecaJorge F J Coelho
Feb 28, 2017·Journal of Advanced Research·Elbadawy A KamounXin Chen

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Citations

Mar 7, 2019·Tissue Engineering. Part a·Franca Nneka Alaribe, Keolebogile Shirley Caroline Mamotswere Motaung
Aug 26, 2020·Journal of Tissue Engineering and Regenerative Medicine·Parichehr Fatehi, Marjan Abbasi
Jul 7, 2019·International Journal of Biological Macromolecules·Ayub AliMd Nurul Islam
Feb 11, 2021·Pharmaceutics·Umile Gianfranco SpizzirriDonatella Restuccia
Jul 1, 2020·Materials Science & Engineering. C, Materials for Biological Applications·Rajalakshmi Ekambaram, Sangeetha Dharmalingam
Aug 8, 2021·Nanomaterials·Honghai LiYanchuan Guo
Aug 9, 2021·Carbohydrate Polymers·Mohamed Ahmed Mohamady HusseinMosaad Megahed
Jul 7, 2021·Journal of Biomaterials Science. Polymer Edition·Somayeh TaymouriArdeshir Talebi

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Methods Mentioned

BETA
scanning electron microscopy

Software Mentioned

SPSS
ImageJ

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