Antimicrobial effects of calcium hydroxide and chlorhexidine on Enterococcus faecalis

Journal of Endodontics
Ronan Jacques Rezende DelgadoNorberti Bernardineli

Abstract

Endodontic treatment is commonly based on nonspecific elimination of intraradicular microorganisms. Although some authors prefer single-visit root canal operations for endodontic treatment, several studies have shown the importance of intracanal medication between sessions to kill microorganisms that biomechanical preparations alone cannot achieve. The purpose of this study was to evaluate the efficacy of calcium hydroxide Ca(OH)(2) and chlorhexidine gel on the elimination of intratubular Enterococcus faecalis. Human uniradicular teeth contaminated with E. faecalis were treated with Ca(OH)(2), 2% chlorhexidine gel, Ca(OH)(2) plus 2% chlorhexidine gel, or saline (0.9% NaCl) as a negative control. Samples obtained at a depth of 0 to 100 mum and 100 to 200 mum from these root canal preparations were analyzed for bacterial load by counting the number of colony-forming units (CFUs) and bacterial viability using fluorescence microscopy. A significant decrease in the number of CFUs and the percentage of viable E. faecalis was observed after treatment with either Ca(OH)(2) or chlorhexidine when compared with the control group. Additionally, chlorhexidine gel had a significantly higher antimicrobial efficacy as measured by the number of...Continue Reading

References

Nov 7, 1999·International Endodontic Journal·J F Siqueira, H P Lopes
May 2, 2000·Applied and Environmental Microbiology·C SignorettoP Canepari
May 3, 2002·International Endodontic Journal·M EvansD Figdor
Nov 23, 2005·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·Joseph A ZerellaLarz S W Spångberg
Sep 26, 2006·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·Brenda Paula Figueiredo de Almeida GomesFrancisco José de Souza Filho
Oct 24, 2007·Oral Microbiology and Immunology·M E ViannaB P F A Gomes
Apr 29, 2008·Brazilian Dental Journal·Francisco José de Souza-FilhoBrenda Paula Figueiredo de Almeida Gomes
Nov 26, 2008·Journal of Endodontics·Raquel Assed Bezerra da SilvaPaulo Tambasco de Oliveira
Jan 23, 2009·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·Morgana E Vianna, Brenda P F A Gomes
Mar 25, 2009·Journal of Clinical Biochemistry and Nutrition·Tomoko NishikawaMasayasu Inoue
Jul 21, 2009·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·B Tugba TurkTansel Ozturk
Jul 22, 2009·International Endodontic Journal·C SathornH Messer

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Citations

Mar 30, 2013·International Journal of Oral Science·Ronan Jacques Rezende DelgadoNorberti Bernardineli
Feb 19, 2016·Indian Journal of Dental Research : Official Publication of Indian Society for Dental Research·Geethu SomanathOurvind J Singh Birring
Dec 17, 2015·Dental Traumatology : Official Publication of International Association for Dental Traumatology·Jeison B Carbajal Mejía, Angela Aguilar Arrieta
Oct 26, 2012·International Endodontic Journal·B Atila-PektaşO Görduysus
Nov 15, 2011·International Endodontic Journal·R K P LimaM Tanomaru-Filho
Aug 14, 2012·Microscopy Research and Technique·Maristela Soares Swerts PereiraMarcos A Rossi
Sep 23, 2014·Australian Endodontic Journal : the Journal of the Australian Society of Endodontology Inc·Maryam JavidiOmid Rajabi
Dec 17, 2014·Lasers in Medical Science·Matheus Franco da FrotaFabio Luis Camargo Villela Berbert
Oct 26, 2016·Journal of Endodontics·Rafaela Fernandes ZancanMarco Antonio Hungaro Duarte
Jan 18, 2017·Journal of Dental Research, Dental Clinics, Dental Prospects·Ali KangarlouOmid Dianat
Jan 1, 2011·Pharmaceutics·Asteria Luzardo AlvarezJosé Blanco Méndez
May 18, 2011·Clinical Oral Investigations·Lamprini KarygianniAli Al-Ahmad
May 31, 2018·Brazilian Oral Research·Rafaela Fernandes ZancanMarco Antonio Hungaro Duarte
Sep 23, 2014·Jundishapur Journal of Natural Pharmaceutical Products·Behrooz EftekharNarges Behrooz
Jan 30, 2015·The Journal of Clinical Pediatric Dentistry·R F MarickarP Neelakantan
Aug 26, 2011·Pharmaceutics·Asteria Luzardo ÁlvarezJosé Blanco Méndez
Nov 1, 2013·The Journal of Contemporary Dental Practice·Resmiye Ebru TiraliAtilla Elhan
Aug 14, 2021·Surgical Infections·Dominique M DockeryDioscaris R Garcia

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